Hereditary multiple exostoses with spine involvement in a 4‐year‐old boy

Hereditary multiple exostosis (HME) is an autosomal dominant disorder characterized by multiple osteochondromas. We describe a case of acute cervical spinal cord compression arising from an exostosis at the lamina of C7 and T1 in a 4‐year‐old Mexican‐American boy with HME. His affected sibling also...

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Bibliographic Details
Published in:American journal of medical genetics. Part A 2010-05, Vol.152A (5), p.1264-1267
Main Authors: Ezra, Navid, Tetteh, Beatrice, Diament, Michael, Jonas, Adam J., Dickson, Patricia
Format: Article
Language:English
Subjects:
Child, Preschool
Exostoses, Multiple Hereditary - diagnosis
Exostoses, Multiple Hereditary - diagnostic imaging
Female
genetics
hereditary multiple exostosis
Humans
Infant, Newborn
Magnetic Resonance Imaging
Male
osteochondroma
Pregnancy
spinal cord compression
Spine - abnormalities
Spine - diagnostic imaging
Tomography, X-Ray Computed
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Summary:Hereditary multiple exostosis (HME) is an autosomal dominant disorder characterized by multiple osteochondromas. We describe a case of acute cervical spinal cord compression arising from an exostosis at the lamina of C7 and T1 in a 4‐year‐old Mexican‐American boy with HME. His affected sibling also displayed spinal cord compression because of a bony exostosis. Acute cervical spinal cord compression resulting from osteochondroma is a serious complication of HME. © 2010 Wiley‐Liss, Inc.
ISSN:1552-4825
1552-4833
DOI:10.1002/ajmg.a.33345