Function, disability, and health-related quality of life after allograft-prosthesis composite reconstructions of the proximal femur

• Published in: Journal of surgical oncology 2008-03, Vol.97 (3), p.210-215
• Main Authors: Biau, David J., Davis, Aileen, Vastel, Laurent, Tomeno, Bernard, Anract, Philippe
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Artificial Limbs; Bone Transplantation; bone tumor; disability; Disability Evaluation; Female; Femoral Neoplasms - pathology; Femoral Neoplasms - physiopathology; Femoral Neoplasms - surgery; Follow-Up Studies; function; Health Status; Humans; Male; Middle Aged; Prosthesis Implantation; Quality of Life; Reconstructive Surgical Procedures; Recovery of Function - physiology; Retrospective Studies; Treatment Outcome; tumor reconstruction
• ISSN: 0022-4790; 1096-9098
• DOI: 10.1002/jso.20936

Background Factors affecting function, disability and health‐related quality of life after allograft‐prosthesis composite reconstructions have been poorly studied. Methods Retrospective study of eighteen patients who underwent reconstruction with proximal femoral allograft‐prosthesis composites and answered questionnaires to assess hip function (Postel and Merle d'Aubigné, self‐reported Harris Hip Score), disability (Toronto Extremity Salvage Score), and health‐related quality of life (SF‐36). Results The median Toronto Extremity Salvage Score was 76 (IQR: 48–85), the median self‐reported Harris Hip Score was 90 (IQR: 48–95) and the median Postel and Merle d'Aubigné score was 17 (IQR: 12–17). Older age, female gender, and presentation with a pathologic fracture were associated with increased disability and poorest function. The median Physical Component Summary score was 44 (IQR: 39–45) and Mental Component Summary scores were 49 (IQR: 46–56). Male gender and recurrence of disease were associated with poorer health‐related quality of life. There was a high degree of correlation between function, disability scores and Physical Component Summary score. Conclusions Patients' characteristics at presentation such as age, gender, and occurrence of a pathologic fracture play an important role in determining disability, function, and health‐related quality of life after allograft‐prosthesis composite reconstruction of the proximal femur. J. Surg. Oncol. 2008;97:210–215. © 2007 Wiley‐Liss, Inc.