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Universal rubella vaccination programme and maternal rubella immune status: A tale of two systems
Abstract Maternal rubella status was compared between local residents with non-residents who delivered in our hospital during 1998–2008. Among the 60,822 women, non-immunity was more common in the non-residents (19.9% versus 8.1%, P < 0.001). Significant difference and positive correlation with a...
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Published in: | Vaccine 2010-03, Vol.28 (10), p.2227-2230 |
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description | Abstract Maternal rubella status was compared between local residents with non-residents who delivered in our hospital during 1998–2008. Among the 60,822 women, non-immunity was more common in the non-residents (19.9% versus 8.1%, P < 0.001). Significant difference and positive correlation with age and parity were found for both groups, but a significant inverse correlation with year-of-birth was found only in the residents. Regression analysis confirmed that birth after 1970 was associated with reduced odds of non-immunity, which indicated that the rubella vaccination programme, introduced since 1978, has succeeded in reducing the incidence of non-immunity to |
doi_str_mv | 10.1016/j.vaccine.2009.12.052 |
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Among the 60,822 women, non-immunity was more common in the non-residents (19.9% versus 8.1%, P < 0.001). Significant difference and positive correlation with age and parity were found for both groups, but a significant inverse correlation with year-of-birth was found only in the residents. Regression analysis confirmed that birth after 1970 was associated with reduced odds of non-immunity, which indicated that the rubella vaccination programme, introduced since 1978, has succeeded in reducing the incidence of non-immunity to <5% in the youngest generation.</description><identifier>ISSN: 0264-410X</identifier><identifier>EISSN: 1873-2518</identifier><identifier>DOI: 10.1016/j.vaccine.2009.12.052</identifier><identifier>PMID: 20060083</identifier><identifier>CODEN: VACCDE</identifier><language>eng</language><publisher>Kidlington: Elsevier Ltd</publisher><subject>Adult ; Age ; Allergy and Immunology ; Antibodies, Viral - blood ; Applied microbiology ; Biological and medical sciences ; Birth ; Ethnicity ; Female ; Fundamental and applied biological sciences. Psychology ; Health facilities ; Hong Kong ; Human viral diseases ; Humans ; Immune status ; Immunity ; Immunization Programs ; Immunoenzyme Techniques ; Immunoglobulin G - blood ; Infections ; Infectious diseases ; Maternal & child health ; Measles ; Medical sciences ; Microbiology ; Mumps ; Population ; Pregnancy ; Pregnant women ; Regression analysis ; Retrospective Studies ; Rubella - immunology ; Rubella - prevention & control ; Rubella immunity ; Rubella vaccination ; Rubella Vaccine - immunology ; Vaccination ; Vaccines ; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) ; Viral diseases ; Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye ; Young Adult</subject><ispartof>Vaccine, 2010-03, Vol.28 (10), p.2227-2230</ispartof><rights>Elsevier Ltd</rights><rights>2010 Elsevier Ltd</rights><rights>2015 INIST-CNRS</rights><rights>Copyright 2010 Elsevier Ltd. All rights reserved.</rights><rights>2010. Elsevier Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c509t-b6f6ad47ea9ec298003246ba8a42267b1d4367c0896738c084e545d2ceb2db793</citedby><cites>FETCH-LOGICAL-c509t-b6f6ad47ea9ec298003246ba8a42267b1d4367c0896738c084e545d2ceb2db793</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22496221$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20060083$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lao, Terence T</creatorcontrib><creatorcontrib>Suen, Stephen S.H</creatorcontrib><creatorcontrib>Leung, Tak Yeung</creatorcontrib><creatorcontrib>Sahota, Daljit S</creatorcontrib><creatorcontrib>Lau, Tze Kin</creatorcontrib><title>Universal rubella vaccination programme and maternal rubella immune status: A tale of two systems</title><title>Vaccine</title><addtitle>Vaccine</addtitle><description>Abstract Maternal rubella status was compared between local residents with non-residents who delivered in our hospital during 1998–2008. Among the 60,822 women, non-immunity was more common in the non-residents (19.9% versus 8.1%, P < 0.001). Significant difference and positive correlation with age and parity were found for both groups, but a significant inverse correlation with year-of-birth was found only in the residents. Regression analysis confirmed that birth after 1970 was associated with reduced odds of non-immunity, which indicated that the rubella vaccination programme, introduced since 1978, has succeeded in reducing the incidence of non-immunity to <5% in the youngest generation.</description><subject>Adult</subject><subject>Age</subject><subject>Allergy and Immunology</subject><subject>Antibodies, Viral - blood</subject><subject>Applied microbiology</subject><subject>Biological and medical sciences</subject><subject>Birth</subject><subject>Ethnicity</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Health facilities</subject><subject>Hong Kong</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Immune status</subject><subject>Immunity</subject><subject>Immunization Programs</subject><subject>Immunoenzyme Techniques</subject><subject>Immunoglobulin G - blood</subject><subject>Infections</subject><subject>Infectious diseases</subject><subject>Maternal & child health</subject><subject>Measles</subject><subject>Medical sciences</subject><subject>Microbiology</subject><subject>Mumps</subject><subject>Population</subject><subject>Pregnancy</subject><subject>Pregnant women</subject><subject>Regression analysis</subject><subject>Retrospective Studies</subject><subject>Rubella - immunology</subject><subject>Rubella - prevention & control</subject><subject>Rubella immunity</subject><subject>Rubella vaccination</subject><subject>Rubella Vaccine - immunology</subject><subject>Vaccination</subject><subject>Vaccines</subject><subject>Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)</subject><subject>Viral diseases</subject><subject>Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye</subject><subject>Young Adult</subject><issn>0264-410X</issn><issn>1873-2518</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><recordid>eNqFkktv1DAUhSMEotPCTwBZQqirhOtHnJhFUVXxkiqxgErsLMe5QR4Sp9jOoPn3OJqBom66upvvHB_fc4viBYWKApVvttXOWOs8VgxAVZRVULNHxYa2DS9ZTdvHxQaYFKWg8P2kOI1xCwA1p-ppcZIlEqDlm8LceLfDEM1IwtLhOBpy8DXJzZ7chvlHMNOExPieTCZh8P-hbpoWjyQmk5b4llySZEYk80DS75nEfUw4xWfFk8GMEZ8f51lx8-H9t6tP5fWXj5-vLq9LW4NKZScHaXrRoFFomWoBOBOyM60RjMmmo73gsrHQKtnwNk-Btah7ZrFjfdcoflacH3xz5l8LxqQnF-0a0-O8RN1kXHIp2odJzjkVDW8y-eoeuZ2XdQNRU6FayqiUkKn6QNkwxxhw0LfBTSbsNQW9lqW3-liWXsvSlOlcVta9PLov3YT9P9XfdjLw-giYaM04BOOti3ccE0oyRjP37sBh3u_OYdDROvQWexfQJt3P7sEoF_cc7Oi8y4_-xD3Gu1_rmAX663pZ62GBAqqkAv4H-AfJMQ</recordid><startdate>20100302</startdate><enddate>20100302</enddate><creator>Lao, Terence T</creator><creator>Suen, Stephen S.H</creator><creator>Leung, Tak Yeung</creator><creator>Sahota, Daljit S</creator><creator>Lau, Tze Kin</creator><general>Elsevier Ltd</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7RV</scope><scope>7T2</scope><scope>7T5</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0R</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2O</scope><scope>M7N</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20100302</creationdate><title>Universal rubella vaccination programme and maternal rubella immune status: A tale of two systems</title><author>Lao, Terence T ; Suen, Stephen S.H ; Leung, Tak Yeung ; Sahota, Daljit S ; Lau, Tze Kin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c509t-b6f6ad47ea9ec298003246ba8a42267b1d4367c0896738c084e545d2ceb2db793</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adult</topic><topic>Age</topic><topic>Allergy and Immunology</topic><topic>Antibodies, Viral - blood</topic><topic>Applied microbiology</topic><topic>Biological and medical sciences</topic><topic>Birth</topic><topic>Ethnicity</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. 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Among the 60,822 women, non-immunity was more common in the non-residents (19.9% versus 8.1%, P < 0.001). Significant difference and positive correlation with age and parity were found for both groups, but a significant inverse correlation with year-of-birth was found only in the residents. Regression analysis confirmed that birth after 1970 was associated with reduced odds of non-immunity, which indicated that the rubella vaccination programme, introduced since 1978, has succeeded in reducing the incidence of non-immunity to <5% in the youngest generation.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><pmid>20060083</pmid><doi>10.1016/j.vaccine.2009.12.052</doi><tpages>4</tpages></addata></record> |
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subjects | Adult Age Allergy and Immunology Antibodies, Viral - blood Applied microbiology Biological and medical sciences Birth Ethnicity Female Fundamental and applied biological sciences. Psychology Health facilities Hong Kong Human viral diseases Humans Immune status Immunity Immunization Programs Immunoenzyme Techniques Immunoglobulin G - blood Infections Infectious diseases Maternal & child health Measles Medical sciences Microbiology Mumps Population Pregnancy Pregnant women Regression analysis Retrospective Studies Rubella - immunology Rubella - prevention & control Rubella immunity Rubella vaccination Rubella Vaccine - immunology Vaccination Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Viral diseases Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye Young Adult |
title | Universal rubella vaccination programme and maternal rubella immune status: A tale of two systems |
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