Anesthetic Barbiturates in Refractory Status Epilepticus

Two patients with previous cerebral damage and seizures and three patients with acute inflammatory cerebral lesions developed status epilepticus. They were unresponsive to standard anticonvulsants, but anesthetic barbiturates (thiopental and pentobarbital) stopped the seizures promptly.

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Bibliographic Details
Published in:Canadian journal of neurological sciences 1980-11, Vol.7 (4), p.291-292
Main Authors: Young, G.B., Blume, W.T., Bolton, C.F., Warren, K.G.
Format: Article
Language:English
Subjects:
Adult
Anticonvulsants - therapeutic use
Brain - metabolism
Female
gamma-Aminobutyric Acid - metabolism
Glutamates - metabolism
Humans
Injections, Intravenous
Male
Middle Aged
Oxygen Consumption
Pentobarbital - therapeutic use
Seizures - metabolism
Status Epilepticus - drug therapy
Thiopental - therapeutic use
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Description
Summary:Two patients with previous cerebral damage and seizures and three patients with acute inflammatory cerebral lesions developed status epilepticus. They were unresponsive to standard anticonvulsants, but anesthetic barbiturates (thiopental and pentobarbital) stopped the seizures promptly.
ISSN:0317-1671
2057-0155
DOI:10.1017/S0317167100022769