Rare extraintestinal infection caused by toxin-producing Clostridium difficile

Toxigenic Clostridium difficile is a well known cause of antibiotic-associated diarrhea mainly among hospitalized patients, at the same time we have little information about extraintestinal infections caused by this bacterium. We report here on rare extraintestinal infection caused by toxigenic C. d...

Full description

Saved in:
Bibliographic Details
Published in:Anaerobe 2010-06, Vol.16 (3), p.301-303
Main Authors: Urbán, Edit, Terhes, Gabriella, Markotics, Attila, Sóki, József, Nagy, Elizabeth
Format: Article
Language:English
Subjects:
Accidents
Adult
Anaerobic cultivation
Anti-Bacterial Agents - therapeutic use
Bacterial Proteins - metabolism
Bacterial Toxins - metabolism
Clostridium difficile
Clostridium difficile - drug effects
Clostridium difficile - isolation & purification
Clostridium difficile - pathogenicity
Enterotoxins - metabolism
Extraintestinal infection
Foot Injuries - drug therapy
Foot Injuries - microbiology
Foot Injuries - surgery
Humans
Male
Toxin detection
Treatment Outcome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Toxigenic Clostridium difficile is a well known cause of antibiotic-associated diarrhea mainly among hospitalized patients, at the same time we have little information about extraintestinal infections caused by this bacterium. We report here on rare extraintestinal infection caused by toxigenic C. difficile: 31-year-old male, accident victim was admitted to the hospital because of polytrauma. Microbiological examination of the pus revealed a toxin-producing C. difficile as an etiologic factor of this infection. Empiric antibiotic treatment with cefuroxime had been administered right after the positive microbiological result. On the basis of antibiotic susceptibility testing, the isolated strain was susceptible to most antimicrobials, except from cefoxitin, thus cefuroxime was changed to imipenem.
ISSN:1075-9964
1095-8274
DOI:10.1016/j.anaerobe.2009.10.004