Zygomycotic invasion of the central nervous system

Zygomycosis is an opportunistic fungal infection that affects the central nervous system (CNS). In this report, we present three cases of zygomycosis with CNS involvement. In two patients zygomycosis developed after neurosurgery, and in the third patient zygomycosis developed after bone marrow trans...

Full description

Saved in:
Bibliographic Details
Published in:Japanese Journal of Radiology 2010-06, Vol.28 (5), p.376-380
Main Authors: Sasaki, Tomoaki, Mineta, Masayuki, Kobayashi, Keigo, Ando, Masakatsu, Obata, Masahiko
Format: Article
Language:English
Subjects:
Adult
Aged
Bone Marrow Transplantation
Brain Diseases - diagnostic imaging
Brain Diseases - etiology
Case Report
Cerebral Infarction - etiology
Female
Humans
Imaging
Medicine
Medicine & Public Health
Middle Aged
Neurosurgical Procedures
Nuclear Medicine
Opportunistic Infections
Postoperative Complications
Radiography
Radiology
Radiotherapy
Zygomycosis - diagnostic imaging
Zygomycosis - etiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Zygomycosis is an opportunistic fungal infection that affects the central nervous system (CNS). In this report, we present three cases of zygomycosis with CNS involvement. In two patients zygomycosis developed after neurosurgery, and in the third patient zygomycosis developed after bone marrow transplantation for leukemia. All patients developed persistent fever and neurological deficits. They presented with progressive cerebral infarction accompanied by hemorrhage. Intraoperative findings and histopathological examinations revealed that zygomycotic hyphae caused mycotic aneurysm, vasculitis, and venous occlusion.
ISSN:1867-1071
1862-5274
1867-108X
DOI:10.1007/s11604-010-0435-z