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Analysis of repeated events
Events that may occur repeatedly for individual subjects are of interest in many medical studies. We review methods of analysis for repeated events, emphasizing that the approach taken in a given study should allow clinical questions to be addressed as directly as possible. Methods based on full mod...
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Published in: | Statistical methods in medical research 2002-04, Vol.11 (2), p.141-166 |
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container_title | Statistical methods in medical research |
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creator | Cook, R J Lawless, J F |
description | Events that may occur repeatedly for individual subjects are of interest in many medical studies. We review methods of analysis for repeated events, emphasizing that the approach taken in a given study should allow clinical questions to be addressed as directly as possible. Methods based on full models for event processes as well as on simpler ‘marginal’ assumptions are considered. The treatment of dependent terminating events related to the recurrent events is also discussed. We apply various methods of analysis to studies involving pulmonary exacerbations in persons with cystic fibrosis, and the occurrence of bone metastases and skeletal events in cancer patients, respectively. Most of the methodology considered can be implemented with existing software. |
doi_str_mv | 10.1191/0962280202sm278ra |
format | article |
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Most of the methodology considered can be implemented with existing software.</description><identifier>ISSN: 0962-2802</identifier><identifier>EISSN: 1477-0334</identifier><identifier>DOI: 10.1191/0962280202sm278ra</identifier><identifier>PMID: 12040694</identifier><language>eng</language><publisher>Thousand Oaks, CA: SAGE Publications</publisher><subject>Asthma - drug therapy ; Asthma - physiopathology ; Biometry ; Bone Neoplasms - secondary ; Cystic Fibrosis - complications ; Cystic Fibrosis - drug therapy ; Humans ; Hydrocephalus - surgery ; Life Change Events ; Lung Diseases - etiology ; Lung Diseases - prevention & control ; Medical research ; Models, Biological ; Poisson Distribution ; Recurrence ; Recurrent events ; Statistical analysis ; Treatment Failure</subject><ispartof>Statistical methods in medical research, 2002-04, Vol.11 (2), p.141-166</ispartof><rights>Arnold 2002</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c492t-2b14ffcdbf548e27b67b97e7c9b8abe5b8244677216db698bd12657cce10e45e3</citedby><cites>FETCH-LOGICAL-c492t-2b14ffcdbf548e27b67b97e7c9b8abe5b8244677216db698bd12657cce10e45e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/217676850?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,12846,21394,21395,27924,27925,30999,31000,33611,33612,34530,34531,43733,44115,79364</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12040694$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cook, R J</creatorcontrib><creatorcontrib>Lawless, J F</creatorcontrib><title>Analysis of repeated events</title><title>Statistical methods in medical research</title><addtitle>Stat Methods Med Res</addtitle><description>Events that may occur repeatedly for individual subjects are of interest in many medical studies. 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subjects | Asthma - drug therapy Asthma - physiopathology Biometry Bone Neoplasms - secondary Cystic Fibrosis - complications Cystic Fibrosis - drug therapy Humans Hydrocephalus - surgery Life Change Events Lung Diseases - etiology Lung Diseases - prevention & control Medical research Models, Biological Poisson Distribution Recurrence Recurrent events Statistical analysis Treatment Failure |
title | Analysis of repeated events |
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