effects of carbon dioxide on measuring cerebral spinal fluid pressure

Purpose The effects of pCO2 on cerebral spinal fluid (CSF) pressure measurement were observed in four patients. Methods Children presenting with either a diagnosis or suspected diagnosis of IIH, who were undergoing lumbar puncture under a general anaesthetic for pressure measurement, were recruited...

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Bibliographic Details
Published in:Child's nervous system 2009-07, Vol.25 (7), p.783-784
Main Authors: Lim, Ming Jin, Lin, Jean-Pierre
Format: Article
Language:English
Subjects:
Brief Communication
Carbon Dioxide
Cerebrospinal Fluid Pressure - physiology
Child
Humans
Intracranial Hypertension - cerebrospinal fluid
Intracranial Hypertension - diagnosis
Intracranial Hypertension - metabolism
Medicine
Medicine & Public Health
Neurosciences
Neurosurgery
Spinal Puncture
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Summary:Purpose The effects of pCO2 on cerebral spinal fluid (CSF) pressure measurement were observed in four patients. Methods Children presenting with either a diagnosis or suspected diagnosis of IIH, who were undergoing lumbar puncture under a general anaesthetic for pressure measurement, were recruited to study the relationship between pCO2 and CSF pressure measurements. Results A rise of end-tidal pCO2 by 1 kPa causes a rise of CSF pressure by 3.5-12 cmH20. Conclusion Controlling of pCO2 is important when measuring CSF pressure to prevent misdiagnosis and over treatment of patients with idiopathic intracranial hypertension (IIH).
ISSN:0256-7040
1433-0350
DOI:10.1007/s00381-009-0902-y