Paget's disease of the nipple diagnosed by MRI

Paget's disease of the breast is a rare manifestation of breast carcinoma. The patient presented with a red lesion of the left nipple-areola complex. Breast physical examination, ultrasonography and mammography were normal bilaterally. Magnetic resonance imaging (MRI) correctly depicted Paget&#...

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Bibliographic Details
Published in:Archives of gynecology and obstetrics 2006-08, Vol.274 (5), p.316-318
Main Authors: Capobianco, Giampiero, Spaliviero, Bernardino, Dessole, Salvatore, Cherchi, Pier Luigi, Marras, Vincenzo, Ambrosini, Guido, Meloni, Francesco, Meloni, Giovanni Battista
Format: Article
Language:English
Subjects:
Biopsy
Breast cancer
Breast Neoplasms - diagnosis
Breast Neoplasms - diagnostic imaging
Breast Neoplasms - pathology
Female
Humans
Magnetic Resonance Imaging
Middle Aged
Nipples - pathology
NMR
Nuclear magnetic resonance
Paget's Disease, Mammary - diagnosis
Paget's Disease, Mammary - diagnostic imaging
Paget's Disease, Mammary - pathology
Radiography
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Summary:Paget's disease of the breast is a rare manifestation of breast carcinoma. The patient presented with a red lesion of the left nipple-areola complex. Breast physical examination, ultrasonography and mammography were normal bilaterally. Magnetic resonance imaging (MRI) correctly depicted Paget's disease of the nipple. Before surgery the patient underwent biopsy of the lesion that showed Paget's disease of the breast associated with an underlying ductal carcinoma in situ. The patient underwent left mastectomy and unilateral axillary lymph node dissection. The patient refused the breast-conserving surgery because she was afraid that she could have a recurrence of the carcinoma. Microscopy of the lesion confirmed the MRI diagnosis. MRI was very useful and accurate to diagnose Paget's disease of the breast without palpable mass, ultrasonographic and mammographic findings.
ISSN:0932-0067
1432-0711
DOI:10.1007/s00404-006-0160-0