Determinants of HIV Seroconversion Among Men Who Have Sex With Men Living in a Low HIV Incidence Population in the Era of Highly Active Antiretroviral Therapies

Objective: To estimate human immunodeficiency virus (HIV) incidence and associated risk factors among men who have sex with men (MSM) participating in the Omega Cohort Study in Montreal, 1996-2003. Methods: Longitudinal study of 1587 MSM seronegative at base-line with ≥1 six-month follow-up visit. M...

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Bibliographic Details
Published in:Sexually transmitted diseases 2008-01, Vol.35 (1), p.25-29
Main Authors: LAVOIE, ELAINE, ALARY, MICHEL, REMIS, ROBERT S., OTIS, JOANNE, VINCELETTE, JEAN, TURMEL, BRUNO, LAVOIE, RENE, MASSE, BENOÎT R., LE CLERC, ROGER
Format: Article
Language:English
Subjects:
Adult
Antiretroviral drugs
Antiretroviral Therapy, Highly Active
Biological and medical sciences
Cohort analysis
Cohort Studies
Confidence intervals
Data analysis
Disease transmission
Drug testing
Epidemiology. Vaccinations
General aspects
Harm reduction
HIV
HIV Seropositivity - blood
HIV Seropositivity - drug therapy
HIV Seropositivity - epidemiology
Homosexuality, Male
Homosexuals
Human immunodeficiency virus
Human infectious diseases. Experimental studies and models
Humans
Incidence
Infectious diseases
Longitudinal Studies
Male
Medical sciences
Prospective Studies
Quebec - epidemiology
Risk factors
Sexual Behavior
Sexual behaviour
Studies
Surveys and Questionnaires
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Summary:Objective: To estimate human immunodeficiency virus (HIV) incidence and associated risk factors among men who have sex with men (MSM) participating in the Omega Cohort Study in Montreal, 1996-2003. Methods: Longitudinal study of 1587 MSM seronegative at base-line with ≥1 six-month follow-up visit. Multivariate Cox regression with time-dependent variables was used for data analysis. Results: HIV incidence was 0.62 per 100 person-years (95% confidence interval: 0.41-0.84). In multivariate analyses compared with subjects not reporting any anal sex with serodiscordant or casual partners, those reporting anal sex with such partners (all P values
ISSN:0148-5717
1537-4521
DOI:10.1097/OLQ.0b013e31814fb113