Genetic study of 15 STRs loci of Identifiler system in Angola population

Abstract Angola is located in the African continent, in the area of southern Africa and has a population of approximately 14 million inhabitants. The Angola population has origin from Occidental and Southern Bantu people that came from the great lakes region, creating the most ever known African mig...

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Bibliographic Details
Published in:Forensic science international : genetics 2010-10, Vol.4 (5), p.e153-e157
Main Authors: Melo, Miguel Manuel, Carvalho, Mónica, Lopes, Virgínia, Anjos, Maria João, Serra, Armando, Vieira, Duarte Nuno, Sequeiros, Jorge, Corte-Real, Francisco
Format: Article
Language:English
Subjects:
Angola
Genetics, Population
Humans
Microsatellite Repeats
Pathology
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Summary:Abstract Angola is located in the African continent, in the area of southern Africa and has a population of approximately 14 million inhabitants. The Angola population has origin from Occidental and Southern Bantu people that came from the great lakes region, creating the most ever known African migration of our days. Allele frequencies for the 15 STRs loci in the AmpFlSTR Identifiler kit (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, HUMTH01, D13S317, D16S539, D2S1338, D19S433, HUMVWA, TPOX, D18S51, D5S818, HUMFIBRA/FGA and including the segment of the X-Y homologous gene amelogenin) were studied for Angola population. The genotype frequency of the 15 STR loci showed no significant deviations from Hardy–Weinberg equilibrium expectations and great values for the combined power of discrimination and combined power of a priori exclusion validate the application of these markers in forensic genetics. Comparative analyses between Angola population data and other relevant population database from Africa, Europe and American are presented.
ISSN:1872-4973
1878-0326
DOI:10.1016/j.fsigen.2010.03.010