Brain F-18 Fluorocholine PET/CT for the Assessment of Optic Pathway Glioma in Neurofibromatosis-1

A 22-year-old man diagnosed with neurofibromatosis-I was admitted to the neurology department because of progressive hemianopsia and chronic headache. Magnetic resonance imaging, magnetic resonance spectroscopy (MRS), and F-18 fluorocholine revealed a splenial mass with imaging features compatible w...

Full description

Saved in:
Bibliographic Details
Published in:Clinical nuclear medicine 2010-10, Vol.35 (10), p.838-839
Main Authors: Roselli, Francesco, Pisciotta, Nicola M, Aniello, Maria S, Niccoli-Asabella, Artor, Defazio, Giovanni, Livrea, Paolo, Rubini, Giuseppe
Format: Article
Language:English
Subjects:
Brain - diagnostic imaging
Choline - analogs & derivatives
Glioma - diagnosis
Glioma - diagnostic imaging
Humans
Male
Neurofibromatosis 1 - diagnosis
Neurofibromatosis 1 - diagnostic imaging
Optic Nerve
Positron-Emission Tomography
Tomography, X-Ray Computed
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A 22-year-old man diagnosed with neurofibromatosis-I was admitted to the neurology department because of progressive hemianopsia and chronic headache. Magnetic resonance imaging, magnetic resonance spectroscopy (MRS), and F-18 fluorocholine revealed a splenial mass with imaging features compatible with malignant astrocytoma. At follow-up examination, the sharp decrease in F-18 fluorocholine uptake and in choline/creatine ratio supported a conservative management. Molecular imaging of optic pathway gliomas may be a valuable tool in the selection of therapeutic options.
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0b013e3181ef0b45