International Workshop at the Nobel Forum, Karolinska Institutet on G protein-coupled receptors: finding the words to describe monomers, oligomers, and their molecular mechanisms and defining their meaning. Can a consensus be reached?

A meeting was held May 19, 2010 at the Karolinski Institute on Nomenclature in Pharmacology. This meeting occurred in conjunction with the Symposium The Changing World of G Protein Coupled Receptors: From Monomers to Dimers and Receptor Mosaics (Higher-order Oligomers) held the previous day at the R...

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Bibliographic Details
Published in:Journal of receptors and signal transduction 2010-10, Vol.30 (5), p.284-286
Main Authors: Kenakin, Terry, Agnati, Luigi F., Caron, Marc, Fredholm, Bertil, Guidoli, Diego, Kobilka, Brian, Lefkowitz, Robert W., Lohse, Martin, Woods, Amina, Fuxe, Kjell
Format: Article
Language:English
Subjects:
Congresses as Topic
Humans
Medicin och hälsovetenskap
Protein Multimerization
Receptors, G-Protein-Coupled - chemistry
Receptors, G-Protein-Coupled - metabolism
Signal Transduction - physiology
Sweden
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Summary:A meeting was held May 19, 2010 at the Karolinski Institute on Nomenclature in Pharmacology. This meeting occurred in conjunction with the Symposium The Changing World of G Protein Coupled Receptors: From Monomers to Dimers and Receptor Mosaics (Higher-order Oligomers) held the previous day at the Royal Swedish Academy of Science. Two broad topics of nomenclature were discussed; ligand nomenclature and the definition of 'receptor-receptor' interactions. This paper summarizes discussions on these topics along with a consensus definition of the term 'receptor-receptor' interaction.
ISSN:1079-9893
1532-4281
1532-4281
DOI:10.3109/10799893.2010.512438