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Metabolic Mapping of the Brain's Response to Visual Stimulation: Studies in Humans

These studies demonstrated increasing glucose metabolic rates in the human primary (PVC) and associative (AVC) visual cortex as the complexity of visual scenes increased. The metabolic response of the AVC increased more rapidly with scene complexity than that of the PVC, indicating the greater invol...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 1981-03, Vol.211 (4489), p.1445-1448
Main Authors: Phelps, Michael E., Kuhl, David E., Mazziotta, John C.
Format: Article
Language:English
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Summary:These studies demonstrated increasing glucose metabolic rates in the human primary (PVC) and associative (AVC) visual cortex as the complexity of visual scenes increased. The metabolic response of the AVC increased more rapidly with scene complexity than that of the PVC, indicating the greater involvement of the higher order AVC for complex visual interpretations. Increases in local metabolic activity by as much as a factor of 2 above that of control subjects with eyes closed indicate the wide range and metabolic reserve of the visual cortex.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.6970412