The reaction to trichophytin in dermatophytoses

The authors investigated the specific immunological competence of 31 patients with dermatophytosis using tricophytin antigen. Among them, 54.8% showed reaction to the delay phase (48 h) in the following proportions: tinea inguinale, 75%; tinea pedis, 61.5%; tinea unguium, 50% and tinea corporis, 20%...

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Bibliographic Details
Published in:Revista do Instituto de Medicina Tropical de São Paulo 1992-11, Vol.34 (6), p.505-509
Main Authors: Vilani-Moreno, F R, de Arruda, M S
Format: Article
Language:Portuguese
Subjects:
Dermatomycoses - diagnosis
Dermatomycoses - immunology
Humans
Hypersensitivity, Delayed - diagnosis
Hypersensitivity, Delayed - immunology
Hypersensitivity, Immediate - diagnosis
Hypersensitivity, Immediate - immunology
Immunity, Cellular
Skin Tests
Tinea - diagnosis
Tinea - immunology
Trichophytin - immunology
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Summary:The authors investigated the specific immunological competence of 31 patients with dermatophytosis using tricophytin antigen. Among them, 54.8% showed reaction to the delay phase (48 h) in the following proportions: tinea inguinale, 75%; tinea pedis, 61.5%; tinea unguium, 50% and tinea corporis, 20%. Other 62.5% showed positive result to the early phase (30 m). The association between these reactions revealed that, although the majority of cases with early positive reaction showed negativity to the delayed reaction, 20.8% presented positively to both phases of the reaction. Out of the non-reactive patients to the delayed phase, 8 were submitted to the other cutaneous tests such as PPD, streptokinase, candidin, vaccinia and DNCB and showed preserved cellular immunity in 75%. These results suggest that, while using this reaction for immunological evaluation of patients with dermatophytosis, one should consider the overall immune status of the patient, the presence of early hypersensibility and the localization of the infection.
ISSN:0036-4665