Frontiers of the Biological Sciences

The history of the molecular revolution in biology is described, emphasizing its dependence on the emergence of bacterial genetics, the fusion of genetics and biochemistry, and the development of greatly improved techniques for studying macromolecules. Central concepts have included molecular inform...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 1980-07, Vol.209 (4452), p.78-89
Main Author: Davis, Bernard D.
Format: Article
Language:English
Subjects:
Allergy and Immunology - trends
Allosteric Regulation
Animal cells
Biological Evolution
Biological research
Biology
Biology - history
Cancer
Cancer research
Cell research
Cells
Chromosome mapping
Cytological research
DNA
DNA - genetics
DNA, Recombinant
Embryology - trends
Enzymes
Gene Expression Regulation
Genes
Genetic Engineering
Genetic recombination
Genetic research
Genetics - trends
History of medicine
History, 20th Century
Immunologic research
Immunological research
Membranes (Biology)
Membranes - physiology
Molecular Biology - trends
Molecular genetics
Molecules
Neoplasms - etiology
Neurobiology
Neurology - trends
Neurons
Nucleic Acid Conformation
P branes
Present and Future Frontiers of the Sciences
Protein Biosynthesis
Protein research
Ribosomes - physiology
Space life sciences
Transcription, Genetic
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Summary:The history of the molecular revolution in biology is described, emphasizing its dependence on the emergence of bacterial genetics, the fusion of genetics and biochemistry, and the development of greatly improved techniques for studying macromolecules. Central concepts have included molecular information transfer, both by nucleic acids and by allosteric proteins; the spontaneous conversion of one-dimensional information into three-dimensional structures; and the extraordinary unity in the molecular mechanisms underlying the rich diversity of biology. The merging of molecular and morphological studies, to yield the very broad field of cell biology, is described more briefly, as are also some present frontiers in several areas of biology that present challenges at other levels of organization.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.7025206