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Augmentation of human natural killer cells by splenopentin analogs
Splenopentin, Arg-Lys-Glu-Val-Tyr (SP-5) and its synthetic analogs; Arg- d-Lys-Glu-Val-Tyr (pentapeptide 1), Lys-Lys-Glu-Val-Tyr ( 2), d-Lys-Lys-Glu-Val-Tyr ( 3), Arg-Lys-Gly-Val-Tyr ( 4), and Arg-Lys-Gln-Val-Tyr ( 5) have been examined for augmentation of human natural killer (NK) cell activity and...
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| Published in: | FEBS letters 1993-02, Vol.317 (1), p.93-95 |
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| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c495O-72b8369fb4107cd6011412b020a3564fb9e2f782d4e1012da42926212b81142f3 |
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| cites | cdi_FETCH-LOGICAL-c495O-72b8369fb4107cd6011412b020a3564fb9e2f782d4e1012da42926212b81142f3 |
| container_end_page | 95 |
| container_issue | 1 |
| container_start_page | 93 |
| container_title | FEBS letters |
| container_volume | 317 |
| creator | Rastogi, A. Singh, V.K. Biswas, S. Haq, W. Mathur, K.B. Agarwal, S.S. |
| description | Splenopentin, Arg-Lys-Glu-Val-Tyr (SP-5) and its synthetic analogs; Arg-
d-Lys-Glu-Val-Tyr (pentapeptide
1), Lys-Lys-Glu-Val-Tyr (
2),
d-Lys-Lys-Glu-Val-Tyr (
3), Arg-Lys-Gly-Val-Tyr (
4), and Arg-Lys-Gln-Val-Tyr (
5) have been examined for augmentation of human natural killer (NK) cell activity and human T-cell transformation response. Pentapeptides
2 and
3 were found to significantly augment the in vitro human NK cell activity. However, none of them had any effect on lymphocyte proliferative responses. |
| doi_str_mv | 10.1016/0014-5793(93)81498-O |
| format | article |
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d-Lys-Glu-Val-Tyr (pentapeptide
1), Lys-Lys-Glu-Val-Tyr (
2),
d-Lys-Lys-Glu-Val-Tyr (
3), Arg-Lys-Gly-Val-Tyr (
4), and Arg-Lys-Gln-Val-Tyr (
5) have been examined for augmentation of human natural killer (NK) cell activity and human T-cell transformation response. Pentapeptides
2 and
3 were found to significantly augment the in vitro human NK cell activity. However, none of them had any effect on lymphocyte proliferative responses.</description><identifier>ISSN: 0014-5793</identifier><identifier>EISSN: 1873-3468</identifier><identifier>DOI: 10.1016/0014-5793(93)81498-O</identifier><identifier>PMID: 8428639</identifier><identifier>CODEN: FEBLAL</identifier><language>eng</language><publisher>Amsterdam: Elsevier B.V</publisher><subject>Adjuvants, Immunologic - pharmacology ; Amino Acid Sequence ; Biological and medical sciences ; Cells, Cultured ; FCS ; foetal calf serum ; Fundamental and applied biological sciences. Psychology ; Fundamental immunology ; Humans ; Immunobiology ; Immunomodulator ; Killer Cells, Natural - drug effects ; Killer Cells, Natural - immunology ; Lymphocyte Activation - drug effects ; Lymphoid cells: ontogeny, maturation, markers, receptors, circulation and recirculation ; Molecular Sequence Data ; natural killer cells ; NK cells ; NK. cell cytotoxicity ; Peptide Fragments - pharmacology ; PHA ; phytohaemagglutinin ; Splenopentin ; T-cell transformation ; Thymopoietin ; Thymopoietins - pharmacology</subject><ispartof>FEBS letters, 1993-02, Vol.317 (1), p.93-95</ispartof><rights>1993</rights><rights>FEBS Letters 317 (1993) 1873-3468 © 2015 Federation of European Biochemical Societies</rights><rights>1993 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c495O-72b8369fb4107cd6011412b020a3564fb9e2f782d4e1012da42926212b81142f3</citedby><cites>FETCH-LOGICAL-c495O-72b8369fb4107cd6011412b020a3564fb9e2f782d4e1012da42926212b81142f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/001457939381498O$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3549,27924,27925,45780</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4557178$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8428639$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rastogi, A.</creatorcontrib><creatorcontrib>Singh, V.K.</creatorcontrib><creatorcontrib>Biswas, S.</creatorcontrib><creatorcontrib>Haq, W.</creatorcontrib><creatorcontrib>Mathur, K.B.</creatorcontrib><creatorcontrib>Agarwal, S.S.</creatorcontrib><title>Augmentation of human natural killer cells by splenopentin analogs</title><title>FEBS letters</title><addtitle>FEBS Lett</addtitle><description>Splenopentin, Arg-Lys-Glu-Val-Tyr (SP-5) and its synthetic analogs; Arg-
d-Lys-Glu-Val-Tyr (pentapeptide
1), Lys-Lys-Glu-Val-Tyr (
2),
d-Lys-Lys-Glu-Val-Tyr (
3), Arg-Lys-Gly-Val-Tyr (
4), and Arg-Lys-Gln-Val-Tyr (
5) have been examined for augmentation of human natural killer (NK) cell activity and human T-cell transformation response. Pentapeptides
2 and
3 were found to significantly augment the in vitro human NK cell activity. However, none of them had any effect on lymphocyte proliferative responses.</description><subject>Adjuvants, Immunologic - pharmacology</subject><subject>Amino Acid Sequence</subject><subject>Biological and medical sciences</subject><subject>Cells, Cultured</subject><subject>FCS</subject><subject>foetal calf serum</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Fundamental immunology</subject><subject>Humans</subject><subject>Immunobiology</subject><subject>Immunomodulator</subject><subject>Killer Cells, Natural - drug effects</subject><subject>Killer Cells, Natural - immunology</subject><subject>Lymphocyte Activation - drug effects</subject><subject>Lymphoid cells: ontogeny, maturation, markers, receptors, circulation and recirculation</subject><subject>Molecular Sequence Data</subject><subject>natural killer cells</subject><subject>NK cells</subject><subject>NK. cell cytotoxicity</subject><subject>Peptide Fragments - pharmacology</subject><subject>PHA</subject><subject>phytohaemagglutinin</subject><subject>Splenopentin</subject><subject>T-cell transformation</subject><subject>Thymopoietin</subject><subject>Thymopoietins - pharmacology</subject><issn>0014-5793</issn><issn>1873-3468</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><recordid>eNqNkEtr3DAUhUVISSePf9CAFyEkC6d62ZI2hSRk2kBgNs1ayPJ1qlSWp5LdMP8-cmaYZSkIhO757tG9B6EvBN8QTOqvGBNeVkKxK8WuJeFKlqsDtCBSsJLxWh6ixR75jI5TesX5LYk6QkeSU1kztUB3t9NLD2E0oxtCMXTFr6k3oQhmnKLxxW_nPcTCgvepaDZFWnsIwzo3uFCYYPzwkk7Rp874BGe7-wQ9Lx9-3v8on1bfH-9vn0rLVbUqBW0kq1XXcIKFbWtMCCe0wRQbVtW8axTQTkjacsjr0dZwqmhNMyIzSTt2gi63vus4_Jkgjbp3aZ7MBBimpEVV1UJQnkG-BW0cUorQ6XV0vYkbTbCeo9NzLnrORefzEZ1e5bbznf_U9NDum3ZZZf1ip5tkje-iCdalPcarShAhM7bcYm_Ow-a_vtbLhzs6C3NdsY_qPM-3rRHkUP86iDpZB8FC6yLYUbeD-_dC787_nGg</recordid><startdate>19930208</startdate><enddate>19930208</enddate><creator>Rastogi, A.</creator><creator>Singh, V.K.</creator><creator>Biswas, S.</creator><creator>Haq, W.</creator><creator>Mathur, K.B.</creator><creator>Agarwal, S.S.</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>6I.</scope><scope>AAFTH</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19930208</creationdate><title>Augmentation of human natural killer cells by splenopentin analogs</title><author>Rastogi, A. ; Singh, V.K. ; Biswas, S. ; Haq, W. ; Mathur, K.B. ; Agarwal, S.S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c495O-72b8369fb4107cd6011412b020a3564fb9e2f782d4e1012da42926212b81142f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Adjuvants, Immunologic - pharmacology</topic><topic>Amino Acid Sequence</topic><topic>Biological and medical sciences</topic><topic>Cells, Cultured</topic><topic>FCS</topic><topic>foetal calf serum</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Fundamental immunology</topic><topic>Humans</topic><topic>Immunobiology</topic><topic>Immunomodulator</topic><topic>Killer Cells, Natural - drug effects</topic><topic>Killer Cells, Natural - immunology</topic><topic>Lymphocyte Activation - drug effects</topic><topic>Lymphoid cells: ontogeny, maturation, markers, receptors, circulation and recirculation</topic><topic>Molecular Sequence Data</topic><topic>natural killer cells</topic><topic>NK cells</topic><topic>NK. cell cytotoxicity</topic><topic>Peptide Fragments - pharmacology</topic><topic>PHA</topic><topic>phytohaemagglutinin</topic><topic>Splenopentin</topic><topic>T-cell transformation</topic><topic>Thymopoietin</topic><topic>Thymopoietins - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rastogi, A.</creatorcontrib><creatorcontrib>Singh, V.K.</creatorcontrib><creatorcontrib>Biswas, S.</creatorcontrib><creatorcontrib>Haq, W.</creatorcontrib><creatorcontrib>Mathur, K.B.</creatorcontrib><creatorcontrib>Agarwal, S.S.</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>FEBS letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rastogi, A.</au><au>Singh, V.K.</au><au>Biswas, S.</au><au>Haq, W.</au><au>Mathur, K.B.</au><au>Agarwal, S.S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Augmentation of human natural killer cells by splenopentin analogs</atitle><jtitle>FEBS letters</jtitle><addtitle>FEBS Lett</addtitle><date>1993-02-08</date><risdate>1993</risdate><volume>317</volume><issue>1</issue><spage>93</spage><epage>95</epage><pages>93-95</pages><issn>0014-5793</issn><eissn>1873-3468</eissn><coden>FEBLAL</coden><abstract>Splenopentin, Arg-Lys-Glu-Val-Tyr (SP-5) and its synthetic analogs; Arg-
d-Lys-Glu-Val-Tyr (pentapeptide
1), Lys-Lys-Glu-Val-Tyr (
2),
d-Lys-Lys-Glu-Val-Tyr (
3), Arg-Lys-Gly-Val-Tyr (
4), and Arg-Lys-Gln-Val-Tyr (
5) have been examined for augmentation of human natural killer (NK) cell activity and human T-cell transformation response. Pentapeptides
2 and
3 were found to significantly augment the in vitro human NK cell activity. However, none of them had any effect on lymphocyte proliferative responses.</abstract><cop>Amsterdam</cop><pub>Elsevier B.V</pub><pmid>8428639</pmid><doi>10.1016/0014-5793(93)81498-O</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0014-5793 |
| ispartof | FEBS letters, 1993-02, Vol.317 (1), p.93-95 |
| issn | 0014-5793 1873-3468 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75567724 |
| source | ScienceDirect Additional Titles |
| subjects | Adjuvants, Immunologic - pharmacology Amino Acid Sequence Biological and medical sciences Cells, Cultured FCS foetal calf serum Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Immunobiology Immunomodulator Killer Cells, Natural - drug effects Killer Cells, Natural - immunology Lymphocyte Activation - drug effects Lymphoid cells: ontogeny, maturation, markers, receptors, circulation and recirculation Molecular Sequence Data natural killer cells NK cells NK. cell cytotoxicity Peptide Fragments - pharmacology PHA phytohaemagglutinin Splenopentin T-cell transformation Thymopoietin Thymopoietins - pharmacology |
| title | Augmentation of human natural killer cells by splenopentin analogs |
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