Haemocompatibility of TI6A14V alloy

TI6A14V alloy has been mainly used as a biomaterlal In the orthopaedic field. The present study describes the surface state of the TI6A14V material and evaluates its in vitro haemocompatibility in terms of protein adsorption, platelet retention and haemolysis. The behaviour of the TI6A14V alloy towa...

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Bibliographic Details
Published in:Biomaterials 1993, Vol.14 (2), p.122-126
Main Authors: Dion, Isabelle, Baquey, Charles, Monties, Jean-Raoul, Havlik, P.
Format: Article
Language:English
Subjects:
Adsorption
Alloys
Biocompatible Materials - pharmacology
Blood Platelets - drug effects
Blood Proteins - drug effects
Blood Proteins - physiology
Fibrinogen - drug effects
Fibrinogen - physiology
haemocompatibility
Heart-Assist Devices
Hemolysis - drug effects
Humans
In Vitro Techniques
Microscopy, Electron, Scanning
Rubber - pharmacology
Serum Albumin - drug effects
Serum Albumin - physiology
Ti alloy
Titanium - chemistry
Titanium - pharmacology
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Summary:TI6A14V alloy has been mainly used as a biomaterlal In the orthopaedic field. The present study describes the surface state of the TI6A14V material and evaluates its in vitro haemocompatibility in terms of protein adsorption, platelet retention and haemolysis. The behaviour of the TI6A14V alloy towards albumin and fibrinogen was compared to that of a reference medical-grade elastomer. The platelet retention test gave better results than those achieved with the elastomer. The haemolysis percentage of the alloy was almost zero. These results indicate that the TI6A14V alloy is well tolerated by blood.
ISSN:0142-9612
1878-5905
DOI:10.1016/0142-9612(93)90222-N