Intensity of Infection in AIDS-Associated Cryptosporidiosis

A fluorescent monoclonal anti-Cryptosporidium antibody was used to count the oocysts in stools of 12 AIDS patients with chronic cryptosporidiosis. Oocyst excretion was present throughout the day in all 12 patients. Stool-to-stool variation in oocyst concentration was within one order of magnitude. S...

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Bibliographic Details
Published in:The Journal of infectious diseases 1993-03, Vol.167 (3), p.704-709
Main Authors: Goodgame, Richard W., Genta, Robert M., White, A. Clinton, Chappell, Cynthia L.
Format: Article
Language:English
Subjects:
AIDS
AIDS-Related Opportunistic Infections
AIDS/HIV
Animals
Antibodies, Monoclonal
Biological and medical sciences
Biopsies
Cryptosporidiosis
Cryptosporidiosis - drug therapy
Cryptosporidiosis - parasitology
Cryptosporidium - growth & development
Diarrhea
Duodenum - pathology
Excretion
Feces - parasitology
Fluorescent Antibody Technique
Histology
Humans
Immunodeficiencies
Immunodeficiencies. Immunoglobulinopathies
Immunopathology
Infections
Internships
Major Articles
Medical sciences
Microscopy, Fluorescence
Oocysts
Paromomycin - therapeutic use
Reproducibility of Results
Specimens
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Description
Summary:A fluorescent monoclonal anti-Cryptosporidium antibody was used to count the oocysts in stools of 12 AIDS patients with chronic cryptosporidiosis. Oocyst excretion was present throughout the day in all 12 patients. Stool-to-stool variation in oocyst concentration was within one order of magnitude. Small variations were also found in daily mean oocyst concentration and total daily oocyst excretion in 3 patients who had multiple 24-h stool collections. However, there was a large patient-to-patient variation in mean oocyst concentration (from
ISSN:0022-1899
1537-6613
DOI:10.1093/infdis/167.3.704