Colonic mucosal pH in humans

Mucosal pH was measured at specific anatomic segments within the colon using a flexible pH probe in patients prepared for colonoscopy. The data revealed similar pH measurements along the length of the colon, irrespective of the presence or absence of colorectal neoplasia. Patients exhibited a relati...

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Bibliographic Details
Published in:Digestive diseases and sciences 1993-03, Vol.38 (3), p.542-545
Main Authors: MCDOUGALL, C. J, WONG, R, SCUDERA, P, LESSER, M, DECOSSE, J. J
Format: Article
Language:English
Subjects:
Biological and medical sciences
Colon - metabolism
Colonic Neoplasms - metabolism
Colonoscopy
Female
Fundamental and applied biological sciences. Psychology
Humans
Hydrogen-Ion Concentration
Intestinal Mucosa - metabolism
Intestine. Mesentery
Male
Middle Aged
Vertebrates: digestive system
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Summary:Mucosal pH was measured at specific anatomic segments within the colon using a flexible pH probe in patients prepared for colonoscopy. The data revealed similar pH measurements along the length of the colon, irrespective of the presence or absence of colorectal neoplasia. Patients exhibited a relatively acidic right colon; a more alkaline transverse, left, and sigmoid colon; and a relatively acidic rectum. There were no apparent gender- or age-related effects on colonic mucosal pH.
ISSN:0163-2116
1573-2568
DOI:10.1007/BF01316512