Long-Standing Bacteremia Caused by Oral Actinobacillus actinomycetemcomitans in a Patient with a Pacemaker

A case of symptomatic Actinobacillus actinomycetemcomitans bacteremia in a patient with an implanted pacemaker is presented. Attacks of fever occurred for at least 1 year. Oral examination revealed a mild form of periodontitis. A. actinomycetemcomitans was isolated from several oral sites. DNA finge...

Full description

Saved in:
Bibliographic Details
Published in:Clinical infectious diseases 1993-02, Vol.16 (2), p.216-218
Main Authors: van Winkelhoff, A. J., Overbeek, B. P., Pavide, M. J. A. M. P., van den Bergh, J. P. A., Ernst, J. P. M. G., de Graaff, J.
Format: Article
Language:English
Subjects:
Actinobacillus actinomycetemcomitans
Actinobacillus Infections - drug therapy
Actinobacillus Infections - etiology
Actinobacillus Infections - microbiology
Aggregatibacter actinomycetemcomitans - classification
Aggregatibacter actinomycetemcomitans - isolation & purification
Amoxicillin - therapeutic use
Artificial pacemakers
Bacteremia
Bacteremia - drug therapy
Bacteremia - etiology
Bacteremia - microbiology
Blood
Clinical Infectious Disease Articles
Drug Therapy, Combination - therapeutic use
Endocarditis
Humans
Infections
Juvenile periodontitis
Male
Metronidazole - therapeutic use
Middle Aged
Mouth
Mouth - microbiology
Pacemaker, Artificial - adverse effects
Periodontal diseases
Periodontitis
Periodontitis - microbiology
Time Factors
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A case of symptomatic Actinobacillus actinomycetemcomitans bacteremia in a patient with an implanted pacemaker is presented. Attacks of fever occurred for at least 1 year. Oral examination revealed a mild form of periodontitis. A. actinomycetemcomitans was isolated from several oral sites. DNA fingerprinting of strains from the blood and the oral cavity showed identical profiles. This finding strongly suggests that the oral cavity was the primary source of A. actinomycetemcomitans bacteremia in this case. The patient was treated with the combination of metronidazole plus amoxicillin for 7 days, which resulted in a rapid cure and elimination of A. actinomycetemcomitans from the blood and the oral cavity.
ISSN:1058-4838
1537-6591
DOI:10.1093/clind/16.2.216