Clostridium perfringens septicemia with massive hemolysis

Massive hemolysis and renal failure are rare complications of infection with Clostridium perfringens, resulting in a very high mortality rate (70-100%). The severity of the infection depends on the presence of underlying conditions such as malignancies and diabetes mellitus. In patients without unde...

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Bibliographic Details
Published in:Infection 1993, Vol.21 (1), p.54-56
Main Authors: ROGSTAD, B, RITLAND, S, LUNDE, S, HAGEN, A. G
Format: Article
Language:English
Subjects:
Anuria - etiology
Bacteremia - complications
Bacteremia - microbiology
Bacterial diseases
Bacterial sepsis
Biological and medical sciences
Clostridium Infections - complications
Clostridium Infections - microbiology
Clostridium perfringens
Hemolysis
Human bacterial diseases
Humans
Infectious diseases
Male
Medical sciences
Middle Aged
Multiple Organ Failure - etiology
Staphylococcal infections, streptococcal infections, pneumococcal infections
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Summary:Massive hemolysis and renal failure are rare complications of infection with Clostridium perfringens, resulting in a very high mortality rate (70-100%). The severity of the infection depends on the presence of underlying conditions such as malignancies and diabetes mellitus. In patients without underlying disorders, massive hemolysis and anuria have been observed in only eight cases, according to recent reports. This case report describes a 61-year-old man who died of C. perfringens septicemia with massive hemolysis and anuria less than 4 h after admittance to the hospital, despite rapid and adequate antibiotic treatment. No focal infection was found.
ISSN:0300-8126
1439-0973
DOI:10.1007/BF01739316