Intron and intronless transcription of the chicken polyubiquitin gene UbII

We have previously reported that the chicken polyubiquitin gene UbII is preferentially expressed during spermatogenesis and we show here that UbII is the predominant polyubiquitin gene expressed in early embryogenesis. Two main initiation sites were detected. Transcription from the initiation site u...

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Bibliographic Details
Published in:FEBS letters 1993-03, Vol.319 (3), p.244-248
Main Authors: Mezquita, Jovita, López-Ibor, Blanca, Pau, Montserrat, Mezquita, Cristóbal
Format: Article
Language:English
Subjects:
Animals
Base Sequence
Biological and medical sciences
Chick Embryo
Chickens - genetics
Cloning, Molecular
Embryogenesis
Fundamental and applied biological sciences. Psychology
Gene Expression
Genes
Initiation site
Introns
Male
Molecular and cellular biology
Molecular genetics
Molecular Sequence Data
Oligodeoxyribonucleotides - chemistry
Polymers
Polyubiquitin
Promoter Regions, Genetic
RNA, Messenger - genetics
Spermatogenesis
Testis - physiology
Transcription, Genetic
Transcription. Transcription factor. Splicing. Rna processing
tRNA
Ubiquitin
Ubiquitin-fusion gene
Ubiquitins - genetics
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Summary:We have previously reported that the chicken polyubiquitin gene UbII is preferentially expressed during spermatogenesis and we show here that UbII is the predominant polyubiquitin gene expressed in early embryogenesis. Two main initiation sites were detected. Transcription from the initiation site used in early embryos results in the presence of an intron in the 5'-untranslated region of the transcripts as has been reported for other polyubiquitin messages. In mature testis, however, the use of a different initiation site, located within the intron, produces intronless transcripts. Distinct promoter sequences, present in each initiation site, may regulate the differential expression observed in this gene.
ISSN:0014-5793
1873-3468
DOI:10.1016/0014-5793(93)80555-9