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Microencapsulation of Methylglyoxal and Two Derivatives
Microcapsules of methylglyoxal, methylglyoxal bis(guanylhydrazone), and methylglyoxal-ascorbic acid condensation complex were prepared and release curves were determined. The effect of various concentrations of hydrochloric acid on the decomposition of the ascorbic acid complex was investigated.
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| Published in: | Journal of pharmaceutical sciences 1981-04, Vol.70 (4), p.385-386 |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c3420-ee9d1bcf101488cf7f9f96a45c92ee2f3bf4c82f9b5c0527773624a3f6c84c4e3 |
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| cites | cdi_FETCH-LOGICAL-c3420-ee9d1bcf101488cf7f9f96a45c92ee2f3bf4c82f9b5c0527773624a3f6c84c4e3 |
| container_end_page | 386 |
| container_issue | 4 |
| container_start_page | 385 |
| container_title | Journal of pharmaceutical sciences |
| container_volume | 70 |
| creator | Nozawa, Yasuo Foxx, Sidney W. |
| description | Microcapsules of methylglyoxal, methylglyoxal bis(guanylhydrazone), and methylglyoxal-ascorbic acid condensation complex were prepared and release curves were determined. The effect of various concentrations of hydrochloric acid on the decomposition of the ascorbic acid complex was investigated. |
| doi_str_mv | 10.1002/jps.2600700410 |
| format | article |
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The effect of various concentrations of hydrochloric acid on the decomposition of the ascorbic acid complex was investigated.</description><identifier>ISSN: 0022-3549</identifier><identifier>EISSN: 1520-6017</identifier><identifier>DOI: 10.1002/jps.2600700410</identifier><identifier>PMID: 7229947</identifier><language>eng</language><publisher>Washington: Elsevier Inc</publisher><subject><![CDATA[Aldehydes - administration & dosage ; Ascorbic Acid - administration & dosage ; Ascorbic Acid - analogs & derivatives ; Capsules ; decomposition in aqueous solution ; Drug Stability ; Guanidines - administration & dosage ; methylglyoxal bis(guanylhydrazone) ; Methylglyoxal-preparation of microcapsules of methylglyoxal ; Methylglyoxal—preparation of microcapsules of methylglyoxal, methylglyoxal bis(guanylhydrazone), or methylglyoxal-ascorbic acid complex, decomposition in aqueous solution ; Microencapsulation-symposium ; Microencapsulation—symposium, preparation of microcapsules of methylglyoxal and derivatives for gradual release in aqueous solution ; Mitoguazone - administration & dosage ; or methylglyoxal-ascorbic acid complex ; preparation of microcapsules of methylglyoxal and derivatives for gradual release in aqueous solution ; Pyruvaldehyde - administration & dosage ; Pyruvaldehyde - analogs & derivatives ; Release-of microcapsules of methylglyoxal ; Release—of microcapsules of methylglyoxal, methylglyoxal bis(guanylhydrazone), or methylglyoxal-ascorbic acid complex, decomposition in aqueous solution ; Solubility ; Space life sciences ; Time Factors]]></subject><ispartof>Journal of pharmaceutical sciences, 1981-04, Vol.70 (4), p.385-386</ispartof><rights>1981 Wiley-Liss, Inc., A Wiley Company</rights><rights>Copyright © 1981 Wiley‐Liss, Inc., A Wiley Company</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3420-ee9d1bcf101488cf7f9f96a45c92ee2f3bf4c82f9b5c0527773624a3f6c84c4e3</citedby><cites>FETCH-LOGICAL-c3420-ee9d1bcf101488cf7f9f96a45c92ee2f3bf4c82f9b5c0527773624a3f6c84c4e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjps.2600700410$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjps.2600700410$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7229947$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nozawa, Yasuo</creatorcontrib><creatorcontrib>Foxx, Sidney W.</creatorcontrib><title>Microencapsulation of Methylglyoxal and Two Derivatives</title><title>Journal of pharmaceutical sciences</title><addtitle>J. Pharm. Sci</addtitle><description>Microcapsules of methylglyoxal, methylglyoxal bis(guanylhydrazone), and methylglyoxal-ascorbic acid condensation complex were prepared and release curves were determined. The effect of various concentrations of hydrochloric acid on the decomposition of the ascorbic acid complex was investigated.</description><subject>Aldehydes - administration & dosage</subject><subject>Ascorbic Acid - administration & dosage</subject><subject>Ascorbic Acid - analogs & derivatives</subject><subject>Capsules</subject><subject>decomposition in aqueous solution</subject><subject>Drug Stability</subject><subject>Guanidines - administration & dosage</subject><subject>methylglyoxal bis(guanylhydrazone)</subject><subject>Methylglyoxal-preparation of microcapsules of methylglyoxal</subject><subject>Methylglyoxal—preparation of microcapsules of methylglyoxal, methylglyoxal bis(guanylhydrazone), or methylglyoxal-ascorbic acid complex, decomposition in aqueous solution</subject><subject>Microencapsulation-symposium</subject><subject>Microencapsulation—symposium, preparation of microcapsules of methylglyoxal and derivatives for gradual release in aqueous solution</subject><subject>Mitoguazone - administration & dosage</subject><subject>or methylglyoxal-ascorbic acid complex</subject><subject>preparation of microcapsules of methylglyoxal and derivatives for gradual release in aqueous solution</subject><subject>Pyruvaldehyde - administration & dosage</subject><subject>Pyruvaldehyde - analogs & derivatives</subject><subject>Release-of microcapsules of methylglyoxal</subject><subject>Release—of microcapsules of methylglyoxal, methylglyoxal bis(guanylhydrazone), or methylglyoxal-ascorbic acid complex, decomposition in aqueous solution</subject><subject>Solubility</subject><subject>Space life sciences</subject><subject>Time Factors</subject><issn>0022-3549</issn><issn>1520-6017</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><recordid>eNqFkU1PGzEQhi3UCgLttbdKe-ptw9jrj_WxCt8CCoKqiIvleMfUdJMN9iaQf4-rjah6qHryYZ73lecZQj5RGFMAtv-4SGMmARQAp7BFRlQwKCVQ9Y6MMsDKSnC9Q3ZTegQACUJsk23FmNZcjYi6CC52OHd2kZat7UM3LzpfXGD_c90-tOvuxbaFnTfF7XNXHGAMq8ysMH0g771tE37cvHvk-9Hh7eSkPP92fDr5el66iud_IOqGTp2nQHldO6-89lpaLpxmiMxXU89dzbyeCgeCKaUqybitvHQ1dxyrPfJl6F3E7mmJqTezkBy2rZ1jt0xGCSlqJmgGxwOY10kpojeLGGY2rg0F89uUyabMH1M58HnTvJzOsHnDN2ryXA_z59Di-j9t5uzq5q_ucsiG1OPLW9bGX0aqSgnz4_LYXN8d3FxO7qW5z3w98JhVrgJGk1zIR8EmRHS9abrwrzVeAXkZlsU</recordid><startdate>198104</startdate><enddate>198104</enddate><creator>Nozawa, Yasuo</creator><creator>Foxx, Sidney W.</creator><general>Elsevier Inc</general><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198104</creationdate><title>Microencapsulation of Methylglyoxal and Two Derivatives</title><author>Nozawa, Yasuo ; Foxx, Sidney W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3420-ee9d1bcf101488cf7f9f96a45c92ee2f3bf4c82f9b5c0527773624a3f6c84c4e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Aldehydes - administration & dosage</topic><topic>Ascorbic Acid - administration & dosage</topic><topic>Ascorbic Acid - analogs & derivatives</topic><topic>Capsules</topic><topic>decomposition in aqueous solution</topic><topic>Drug Stability</topic><topic>Guanidines - administration & dosage</topic><topic>methylglyoxal bis(guanylhydrazone)</topic><topic>Methylglyoxal-preparation of microcapsules of methylglyoxal</topic><topic>Methylglyoxal—preparation of microcapsules of methylglyoxal, methylglyoxal bis(guanylhydrazone), or methylglyoxal-ascorbic acid complex, decomposition in aqueous solution</topic><topic>Microencapsulation-symposium</topic><topic>Microencapsulation—symposium, preparation of microcapsules of methylglyoxal and derivatives for gradual release in aqueous solution</topic><topic>Mitoguazone - administration & dosage</topic><topic>or methylglyoxal-ascorbic acid complex</topic><topic>preparation of microcapsules of methylglyoxal and derivatives for gradual release in aqueous solution</topic><topic>Pyruvaldehyde - administration & dosage</topic><topic>Pyruvaldehyde - analogs & derivatives</topic><topic>Release-of microcapsules of methylglyoxal</topic><topic>Release—of microcapsules of methylglyoxal, methylglyoxal bis(guanylhydrazone), or methylglyoxal-ascorbic acid complex, decomposition in aqueous solution</topic><topic>Solubility</topic><topic>Space life sciences</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nozawa, Yasuo</creatorcontrib><creatorcontrib>Foxx, Sidney W.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of pharmaceutical sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nozawa, Yasuo</au><au>Foxx, Sidney W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Microencapsulation of Methylglyoxal and Two Derivatives</atitle><jtitle>Journal of pharmaceutical sciences</jtitle><addtitle>J. Pharm. Sci</addtitle><date>1981-04</date><risdate>1981</risdate><volume>70</volume><issue>4</issue><spage>385</spage><epage>386</epage><pages>385-386</pages><issn>0022-3549</issn><eissn>1520-6017</eissn><abstract>Microcapsules of methylglyoxal, methylglyoxal bis(guanylhydrazone), and methylglyoxal-ascorbic acid condensation complex were prepared and release curves were determined. The effect of various concentrations of hydrochloric acid on the decomposition of the ascorbic acid complex was investigated.</abstract><cop>Washington</cop><pub>Elsevier Inc</pub><pmid>7229947</pmid><doi>10.1002/jps.2600700410</doi><tpages>2</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-3549 |
| ispartof | Journal of pharmaceutical sciences, 1981-04, Vol.70 (4), p.385-386 |
| issn | 0022-3549 1520-6017 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75658251 |
| source | Wiley Blackwell Single Titles |
| subjects | Aldehydes - administration & dosage Ascorbic Acid - administration & dosage Ascorbic Acid - analogs & derivatives Capsules decomposition in aqueous solution Drug Stability Guanidines - administration & dosage methylglyoxal bis(guanylhydrazone) Methylglyoxal-preparation of microcapsules of methylglyoxal Methylglyoxal—preparation of microcapsules of methylglyoxal, methylglyoxal bis(guanylhydrazone), or methylglyoxal-ascorbic acid complex, decomposition in aqueous solution Microencapsulation-symposium Microencapsulation—symposium, preparation of microcapsules of methylglyoxal and derivatives for gradual release in aqueous solution Mitoguazone - administration & dosage or methylglyoxal-ascorbic acid complex preparation of microcapsules of methylglyoxal and derivatives for gradual release in aqueous solution Pyruvaldehyde - administration & dosage Pyruvaldehyde - analogs & derivatives Release-of microcapsules of methylglyoxal Release—of microcapsules of methylglyoxal, methylglyoxal bis(guanylhydrazone), or methylglyoxal-ascorbic acid complex, decomposition in aqueous solution Solubility Space life sciences Time Factors |
| title | Microencapsulation of Methylglyoxal and Two Derivatives |
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