Study of distant interactions of LCR from the Drosophila melanogaster locus CUT

The goal of this work was to study the possibility of interaction of a short DNA sequence from LCR of Drosophila locus cut, which contains the FT (FT, forum terminus) sequences, with known promoters of this locus. The obtained data confirm the assumption that LCR affects its target genes via formati...

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Bibliographic Details
Published in:Doklady. Biochemistry and biophysics 2010-06, Vol.432 (1), p.102-105
Main Authors: Sosin, D. V., Moiseeva, E. D., Tchurikov, N. A.
Format: Article
Language:English
Subjects:
Animals
Base Sequence
Biochemistry
Biological and Medical Physics
Biomedical and Life Sciences
Biophysics
Biophysics and Molecular Biology
Deoxyribonucleic acid
DNA
DNA Primers - genetics
Drosophila melanogaster
Drosophila melanogaster - genetics
Drosophila Proteins - genetics
Gene amplification
Gene expression
Gene Expression Regulation
Genes, Insect
Homeodomain Proteins - genetics
Insects
Life Sciences
Locus Control Region
Molecular Sequence Data
Nuclear Proteins - genetics
Promoter Regions, Genetic
Transcription Factors - genetics
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Summary:The goal of this work was to study the possibility of interaction of a short DNA sequence from LCR of Drosophila locus cut, which contains the FT (FT, forum terminus) sequences, with known promoters of this locus. The obtained data confirm the assumption that LCR affects its target genes via formation of loop contacts with promoters as well as provide the ground for the search for analogous sequences in other known LCRs.
ISSN:1607-6729
1608-3091
DOI:10.1134/S1607672910030026