Loading…
Treatment of acute cutaneous leishmaniasis with intralesional injection of meglumine antimoniate: comparison of conventional technique with mesotherapy gun
The gold standard treatment of Old World leishmaniasis, a common tropical parasitic infestation, is intralesional meglumine antimoniate injection. Mesotherapy is a new minimally invasive method of administration of variable substances to the skin. Comparison of the efficacy and adverse effects of tr...
Saved in:
| Published in: | International journal of dermatology 2010-09, Vol.49 (9), p.1034-1037 |
|---|---|
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | |
|---|---|
| cites | |
| container_end_page | 1037 |
| container_issue | 9 |
| container_start_page | 1034 |
| container_title | International journal of dermatology |
| container_volume | 49 |
| creator | MANSOUR NASSIRI KASHANI SADR, Bardia MOHAMMAD ALI NILFOROUSHZADEH ARASTEH, Mahfar BABAKOOHI, Shahab FIROOZ, Alireza |
| description | The gold standard treatment of Old World leishmaniasis, a common tropical parasitic infestation, is intralesional meglumine antimoniate injection. Mesotherapy is a new minimally invasive method of administration of variable substances to the skin.
Comparison of the efficacy and adverse effects of treatment of leishmaniasis with intralesional injection of meglumine antimoniate using conventional method and mesotherapy method.
Eighty-five patients with proven leishmaniasis were recruited and randomly treated by one of the two methods, either by conventional injection or by mesotherapy administration weekly. Lesion characteristics were evaluated at every treatment session as well as 1 week, 1 month and 3 months after cessation of treatment.
The improvement in lesions was similar in both groups, while it was noted sooner in mesotherapy group with less amount of drug usage (P = 0.005 and 0.016 respectively). Also, patients treated with mesotherapy experienced less pain severity (P = 0.005).
Mesotherapy is a safe and effective method of meglumine antimoniate injection for the treatment of cutaneous leishmaniasis and is less painful. |
| doi_str_mv | 10.1111/j.1365-4632.2010.04523.x |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_756659359</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>756659359</sourcerecordid><originalsourceid>FETCH-LOGICAL-p240t-937f6af08aef07077e69268274462ac5d0613bec4eb510cc7b5206bfef44bc433</originalsourceid><addsrcrecordid>eNpFkM1u2zAMx4Vhw5KmfYVBl2Inp_p2vFsRrB9AgF3Sc0ArdKLAkj1LXttn6ctOg7NWICSR_P1JgoRQzpY8n5vTkkujC2WkWAqWo0xpIZcvn8j8PfGZzBnjvKiYrmbkIsZTdqXg6iuZCbZaSWH0nLxtB4TkMSTaNRTsmJDmCwJ2Y6Qtunj0EBxEF-mzS0fqQhqgxei6AG32TmhT_v9Tezy0o3cBKYTkfJdlCX9Q2_keBhcnyHbhT-42yRPaY3C_R5xqe4xdOuIA_Ss9jOGSfGmgjXh1fhfk6e7ndv1QbH7dP65vN0UvFEtFJcvGQMNWgA0rWVmiqYRZiVIpI8DqPTNc1mgV1poza8taC2bqBhulaqukXJDvU91-6PIsMe28ixbbdtrCrtTG6EpmW5BvZ3KsPe53_eA8DK-7__vMwPUZgGihbQYI1sUPTnKjmTbyL__Hi00</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>756659359</pqid></control><display><type>article</type><title>Treatment of acute cutaneous leishmaniasis with intralesional injection of meglumine antimoniate: comparison of conventional technique with mesotherapy gun</title><source>Wiley-Blackwell Read & Publish Collection</source><creator>MANSOUR NASSIRI KASHANI ; SADR, Bardia ; MOHAMMAD ALI NILFOROUSHZADEH ; ARASTEH, Mahfar ; BABAKOOHI, Shahab ; FIROOZ, Alireza</creator><creatorcontrib>MANSOUR NASSIRI KASHANI ; SADR, Bardia ; MOHAMMAD ALI NILFOROUSHZADEH ; ARASTEH, Mahfar ; BABAKOOHI, Shahab ; FIROOZ, Alireza</creatorcontrib><description>The gold standard treatment of Old World leishmaniasis, a common tropical parasitic infestation, is intralesional meglumine antimoniate injection. Mesotherapy is a new minimally invasive method of administration of variable substances to the skin.
Comparison of the efficacy and adverse effects of treatment of leishmaniasis with intralesional injection of meglumine antimoniate using conventional method and mesotherapy method.
Eighty-five patients with proven leishmaniasis were recruited and randomly treated by one of the two methods, either by conventional injection or by mesotherapy administration weekly. Lesion characteristics were evaluated at every treatment session as well as 1 week, 1 month and 3 months after cessation of treatment.
The improvement in lesions was similar in both groups, while it was noted sooner in mesotherapy group with less amount of drug usage (P = 0.005 and 0.016 respectively). Also, patients treated with mesotherapy experienced less pain severity (P = 0.005).
Mesotherapy is a safe and effective method of meglumine antimoniate injection for the treatment of cutaneous leishmaniasis and is less painful.</description><identifier>ISSN: 0011-9059</identifier><identifier>EISSN: 1365-4632</identifier><identifier>DOI: 10.1111/j.1365-4632.2010.04523.x</identifier><identifier>PMID: 20883265</identifier><identifier>CODEN: IJDEBB</identifier><language>eng</language><publisher>Oxford: Blackwell</publisher><subject>Acute Disease ; Adolescent ; Adult ; Biological and medical sciences ; Child ; Dermatology ; Female ; Human protozoal diseases ; Humans ; Infectious diseases ; Injections, Intralesional - instrumentation ; Injections, Intralesional - methods ; Leishmaniasis, Cutaneous - drug therapy ; Leshmaniasis ; Male ; Medical sciences ; Meglumine - administration & dosage ; Mesotherapy - instrumentation ; Organometallic Compounds - administration & dosage ; Pain - prevention & control ; Parasitic diseases ; Protozoal diseases ; Treatment Outcome ; Young Adult</subject><ispartof>International journal of dermatology, 2010-09, Vol.49 (9), p.1034-1037</ispartof><rights>2015 INIST-CNRS</rights><rights>2010 The International Society of Dermatology.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23165056$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20883265$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MANSOUR NASSIRI KASHANI</creatorcontrib><creatorcontrib>SADR, Bardia</creatorcontrib><creatorcontrib>MOHAMMAD ALI NILFOROUSHZADEH</creatorcontrib><creatorcontrib>ARASTEH, Mahfar</creatorcontrib><creatorcontrib>BABAKOOHI, Shahab</creatorcontrib><creatorcontrib>FIROOZ, Alireza</creatorcontrib><title>Treatment of acute cutaneous leishmaniasis with intralesional injection of meglumine antimoniate: comparison of conventional technique with mesotherapy gun</title><title>International journal of dermatology</title><addtitle>Int J Dermatol</addtitle><description>The gold standard treatment of Old World leishmaniasis, a common tropical parasitic infestation, is intralesional meglumine antimoniate injection. Mesotherapy is a new minimally invasive method of administration of variable substances to the skin.
Comparison of the efficacy and adverse effects of treatment of leishmaniasis with intralesional injection of meglumine antimoniate using conventional method and mesotherapy method.
Eighty-five patients with proven leishmaniasis were recruited and randomly treated by one of the two methods, either by conventional injection or by mesotherapy administration weekly. Lesion characteristics were evaluated at every treatment session as well as 1 week, 1 month and 3 months after cessation of treatment.
The improvement in lesions was similar in both groups, while it was noted sooner in mesotherapy group with less amount of drug usage (P = 0.005 and 0.016 respectively). Also, patients treated with mesotherapy experienced less pain severity (P = 0.005).
Mesotherapy is a safe and effective method of meglumine antimoniate injection for the treatment of cutaneous leishmaniasis and is less painful.</description><subject>Acute Disease</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Dermatology</subject><subject>Female</subject><subject>Human protozoal diseases</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Injections, Intralesional - instrumentation</subject><subject>Injections, Intralesional - methods</subject><subject>Leishmaniasis, Cutaneous - drug therapy</subject><subject>Leshmaniasis</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Meglumine - administration & dosage</subject><subject>Mesotherapy - instrumentation</subject><subject>Organometallic Compounds - administration & dosage</subject><subject>Pain - prevention & control</subject><subject>Parasitic diseases</subject><subject>Protozoal diseases</subject><subject>Treatment Outcome</subject><subject>Young Adult</subject><issn>0011-9059</issn><issn>1365-4632</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><recordid>eNpFkM1u2zAMx4Vhw5KmfYVBl2Inp_p2vFsRrB9AgF3Sc0ArdKLAkj1LXttn6ctOg7NWICSR_P1JgoRQzpY8n5vTkkujC2WkWAqWo0xpIZcvn8j8PfGZzBnjvKiYrmbkIsZTdqXg6iuZCbZaSWH0nLxtB4TkMSTaNRTsmJDmCwJ2Y6Qtunj0EBxEF-mzS0fqQhqgxei6AG32TmhT_v9Tezy0o3cBKYTkfJdlCX9Q2_keBhcnyHbhT-42yRPaY3C_R5xqe4xdOuIA_Ss9jOGSfGmgjXh1fhfk6e7ndv1QbH7dP65vN0UvFEtFJcvGQMNWgA0rWVmiqYRZiVIpI8DqPTNc1mgV1poza8taC2bqBhulaqukXJDvU91-6PIsMe28ixbbdtrCrtTG6EpmW5BvZ3KsPe53_eA8DK-7__vMwPUZgGihbQYI1sUPTnKjmTbyL__Hi00</recordid><startdate>20100901</startdate><enddate>20100901</enddate><creator>MANSOUR NASSIRI KASHANI</creator><creator>SADR, Bardia</creator><creator>MOHAMMAD ALI NILFOROUSHZADEH</creator><creator>ARASTEH, Mahfar</creator><creator>BABAKOOHI, Shahab</creator><creator>FIROOZ, Alireza</creator><general>Blackwell</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20100901</creationdate><title>Treatment of acute cutaneous leishmaniasis with intralesional injection of meglumine antimoniate: comparison of conventional technique with mesotherapy gun</title><author>MANSOUR NASSIRI KASHANI ; SADR, Bardia ; MOHAMMAD ALI NILFOROUSHZADEH ; ARASTEH, Mahfar ; BABAKOOHI, Shahab ; FIROOZ, Alireza</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p240t-937f6af08aef07077e69268274462ac5d0613bec4eb510cc7b5206bfef44bc433</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Acute Disease</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Dermatology</topic><topic>Female</topic><topic>Human protozoal diseases</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Injections, Intralesional - instrumentation</topic><topic>Injections, Intralesional - methods</topic><topic>Leishmaniasis, Cutaneous - drug therapy</topic><topic>Leshmaniasis</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Meglumine - administration & dosage</topic><topic>Mesotherapy - instrumentation</topic><topic>Organometallic Compounds - administration & dosage</topic><topic>Pain - prevention & control</topic><topic>Parasitic diseases</topic><topic>Protozoal diseases</topic><topic>Treatment Outcome</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MANSOUR NASSIRI KASHANI</creatorcontrib><creatorcontrib>SADR, Bardia</creatorcontrib><creatorcontrib>MOHAMMAD ALI NILFOROUSHZADEH</creatorcontrib><creatorcontrib>ARASTEH, Mahfar</creatorcontrib><creatorcontrib>BABAKOOHI, Shahab</creatorcontrib><creatorcontrib>FIROOZ, Alireza</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MANSOUR NASSIRI KASHANI</au><au>SADR, Bardia</au><au>MOHAMMAD ALI NILFOROUSHZADEH</au><au>ARASTEH, Mahfar</au><au>BABAKOOHI, Shahab</au><au>FIROOZ, Alireza</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Treatment of acute cutaneous leishmaniasis with intralesional injection of meglumine antimoniate: comparison of conventional technique with mesotherapy gun</atitle><jtitle>International journal of dermatology</jtitle><addtitle>Int J Dermatol</addtitle><date>2010-09-01</date><risdate>2010</risdate><volume>49</volume><issue>9</issue><spage>1034</spage><epage>1037</epage><pages>1034-1037</pages><issn>0011-9059</issn><eissn>1365-4632</eissn><coden>IJDEBB</coden><abstract>The gold standard treatment of Old World leishmaniasis, a common tropical parasitic infestation, is intralesional meglumine antimoniate injection. Mesotherapy is a new minimally invasive method of administration of variable substances to the skin.
Comparison of the efficacy and adverse effects of treatment of leishmaniasis with intralesional injection of meglumine antimoniate using conventional method and mesotherapy method.
Eighty-five patients with proven leishmaniasis were recruited and randomly treated by one of the two methods, either by conventional injection or by mesotherapy administration weekly. Lesion characteristics were evaluated at every treatment session as well as 1 week, 1 month and 3 months after cessation of treatment.
The improvement in lesions was similar in both groups, while it was noted sooner in mesotherapy group with less amount of drug usage (P = 0.005 and 0.016 respectively). Also, patients treated with mesotherapy experienced less pain severity (P = 0.005).
Mesotherapy is a safe and effective method of meglumine antimoniate injection for the treatment of cutaneous leishmaniasis and is less painful.</abstract><cop>Oxford</cop><pub>Blackwell</pub><pmid>20883265</pmid><doi>10.1111/j.1365-4632.2010.04523.x</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0011-9059 |
| ispartof | International journal of dermatology, 2010-09, Vol.49 (9), p.1034-1037 |
| issn | 0011-9059 1365-4632 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_756659359 |
| source | Wiley-Blackwell Read & Publish Collection |
| subjects | Acute Disease Adolescent Adult Biological and medical sciences Child Dermatology Female Human protozoal diseases Humans Infectious diseases Injections, Intralesional - instrumentation Injections, Intralesional - methods Leishmaniasis, Cutaneous - drug therapy Leshmaniasis Male Medical sciences Meglumine - administration & dosage Mesotherapy - instrumentation Organometallic Compounds - administration & dosage Pain - prevention & control Parasitic diseases Protozoal diseases Treatment Outcome Young Adult |
| title | Treatment of acute cutaneous leishmaniasis with intralesional injection of meglumine antimoniate: comparison of conventional technique with mesotherapy gun |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T11%3A52%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Treatment%20of%20acute%20cutaneous%20leishmaniasis%20with%20intralesional%20injection%20of%20meglumine%20antimoniate:%20comparison%20of%20conventional%20technique%20with%20mesotherapy%20gun&rft.jtitle=International%20journal%20of%20dermatology&rft.au=MANSOUR%20NASSIRI%20KASHANI&rft.date=2010-09-01&rft.volume=49&rft.issue=9&rft.spage=1034&rft.epage=1037&rft.pages=1034-1037&rft.issn=0011-9059&rft.eissn=1365-4632&rft.coden=IJDEBB&rft_id=info:doi/10.1111/j.1365-4632.2010.04523.x&rft_dat=%3Cproquest_pubme%3E756659359%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-p240t-937f6af08aef07077e69268274462ac5d0613bec4eb510cc7b5206bfef44bc433%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=756659359&rft_id=info:pmid/20883265&rfr_iscdi=true |