Association of anti-cardiolipin antibodies with vascular thrombosis and neurological manifestation of Behçets disease

We have studied 44 patients with Behçet's Disease (BD) to look for any correlation of arterial and venous thrombosis or central nervous system (CNS) manifestations with anti-cardiolipin antibodies (ACLA). Twenty patients were positive for ACLA by MELISA method. Ten patients had IgG antibody, fo...

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Bibliographic Details
Published in:Clinical rheumatology 1993-03, Vol.12 (1), p.28-30
Main Authors: al-Dalaan, A N, al-Ballaa, S R, al-Janadi, M A, Bohlega, S, Bahabri, S
Format: Article
Language:English
Subjects:
Antibodies, Anticardiolipin - analysis
Behcet Syndrome - complications
Enzyme-Linked Immunosorbent Assay
Humans
Immunoglobulin G - analysis
Immunoglobulin M - analysis
Nervous System Diseases - etiology
Nervous System Diseases - immunology
Thrombosis - etiology
Thrombosis - immunology
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Summary:We have studied 44 patients with Behçet's Disease (BD) to look for any correlation of arterial and venous thrombosis or central nervous system (CNS) manifestations with anti-cardiolipin antibodies (ACLA). Twenty patients were positive for ACLA by MELISA method. Ten patients had IgG antibody, four had IgM and six had both IgG and IgM. Of these patients, 11 had a history of vascular thrombosis and thrombophlebitis and nine had CNS manifestations. The association of ACLA with vascular thrombosis or CNS manifestation of Behçet's disease was statistically not significant.
ISSN:0770-3198
1434-9949
DOI:10.1007/BF02231554