Cerebral vasculitis in acute post-streptococcal glomerulonephritis

Neurological complications in acute post-streptococcal glomerulonephritis (APSGN) have been traditionally attributed to hypertensive encephalopathy. A 9-year-old girl with biopsy-documented APSGN developed seizures at a time she was normotensive and biochemically well balanced. Computed tomography o...

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Bibliographic Details
Published in:Pediatric nephrology (Berlin, West) West), 1993-04, Vol.7 (2), p.194-195
Main Authors: KAPLAN, R. A, ZWICK, D. L, HELLERSTEIN, S, WARADY, B. A, ALON, U
Format: Article
Language:English
Subjects:
Acute Disease
Biological and medical sciences
Brain Diseases - complications
Brain Diseases - diagnostic imaging
Child
Electroencephalography
Female
Glomerulonephritis
Glomerulonephritis - complications
Glomerulonephritis - microbiology
Humans
Medical sciences
Nephrology. Urinary tract diseases
Nephropathies. Renovascular diseases. Renal failure
Seizures - diagnosis
Streptococcal Infections - complications
Tomography, X-Ray Computed
Vasculitis - complications
Vasculitis - diagnostic imaging
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Summary:Neurological complications in acute post-streptococcal glomerulonephritis (APSGN) have been traditionally attributed to hypertensive encephalopathy. A 9-year-old girl with biopsy-documented APSGN developed seizures at a time she was normotensive and biochemically well balanced. Computed tomography of her brain was consistent with vasculitis, a finding which was also clinically supported by apparent vasculitic involvement of other organ systems. All clinical, laboratory and radiological abnormalities resolved with recovery from the APSGN. We suggest that on rare occasions neurological complications in APSGN may result from involvement of the central nervous system in multiorgan transient vasculitis.
ISSN:0931-041X
1432-198X
DOI:10.1007/BF00864396