An experimentally induced phlegmonous abscess by a strain of Bacteroides gingivalis in guinea pigs and mice

The virulence of B. gingivalis strain W83 was studied in an experimental animal model. Cells grown overnight, washed and resuspended in broth, were injected intradermally or subcutaneously in the back of guinea pigs, rats and mice. This strain proved to be very virulent, causing a severe phlegmonous...

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Bibliographic Details
Published in:Antonie van Leeuwenhoek 1981-01, Vol.47 (1), p.1-9
Main Authors: Kastelein, P, van Steenbergen, T J, Bras, J M, de Graaff, J
Format: Article
Language:English
Subjects:
Abscess - microbiology
Abscess - pathology
Animals
Bacteroides - pathogenicity
Bacteroides Infections - microbiology
Bacteroides Infections - pathology
Guinea Pigs
Inflammation
Male
Mice
Necrosis
Rats
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Summary:The virulence of B. gingivalis strain W83 was studied in an experimental animal model. Cells grown overnight, washed and resuspended in broth, were injected intradermally or subcutaneously in the back of guinea pigs, rats and mice. This strain proved to be very virulent, causing a severe phlegmonous abscess in guinea pigs. Also in mice, which are thought to be resistant to infections with black-pigmented Bacteroides strains, the same type of infection could be induced. Rats proved to be rather insensitive. The model presented can be used as a simple virulence test for these anaerobic bacteria.
ISSN:0003-6072
1572-9699
DOI:10.1007/BF00399062