Differential Induction of Mn-containing Superoxide Dismutase by Paraquat in Peripheral Lymphocytes of Normal Subjects and Gastric Cancer Patients

Reactive oxygen species (ROS) cause macromolecular damage and may play an important role in tumor development. Superoxide dismutase (SOD) and metallothionein (MT) serve as initial and final defense mechanisms, respectively, aganist ROS.

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Bibliographic Details
Published in:Molecules and cells 2003-08, Vol.16 (1), p.13-18
Main Authors: Lee, T.B, Lim, D.Y, Jeon, H.J.)Min, Y.D, Kim, K.C, Kim, K.J, Choi, C.H. (Chosun University Medical School, Gwangju, Republic of Korea)
Format: Article
Language:English
Subjects:
Adult
Aged
Enzyme Induction
Female
Fluorescent Dyes - metabolism
Humans
Lymphocytes - metabolism
Male
Metallothionein - genetics
Metallothionein - metabolism
Middle Aged
Oxidative Stress
PARAQUAT
Paraquat - pharmacology
Reactive Oxygen Species - metabolism
RNA, Messenger - metabolism
Stomach Neoplasms - metabolism
Superoxide Dismutase - biosynthesis
Superoxide Dismutase - genetics
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Description
Summary:Reactive oxygen species (ROS) cause macromolecular damage and may play an important role in tumor development. Superoxide dismutase (SOD) and metallothionein (MT) serve as initial and final defense mechanisms, respectively, aganist ROS.
ISSN:1016-8478
DOI:10.1016/S1016-8478(23)13759-9