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Diameter of the Cell-to-Cell Junctional Membrane Channels as Probed with Neutral Molecules
The cell-to-cell channels in the junctions of an insect salivary gland and of insect and mammalian cells in culture were probed with fluorescent molecules--neutral linear oligosaccharides, neutral branched glycopeptides, and charged linear peptides. From the molecular dimensions of the largest perme...
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Published in: | Science (American Association for the Advancement of Science) 1981-07, Vol.213 (4507), p.551-553 |
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cited_by | cdi_FETCH-LOGICAL-c410t-ecd8099a786b41bded615e6832f12eacafc215e2b0eac87687a27d82378676f13 |
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container_end_page | 553 |
container_issue | 4507 |
container_start_page | 551 |
container_title | Science (American Association for the Advancement of Science) |
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creator | Schwarzmann, G. Wiegandt, H. Rose, B. Zimmerman, A. Ben-Haim, D. Loewenstein, W. R. |
description | The cell-to-cell channels in the junctions of an insect salivary gland and of insect and mammalian cells in culture were probed with fluorescent molecules--neutral linear oligosaccharides, neutral branched glycopeptides, and charged linear peptides. From the molecular dimensions of the largest permeants and smallest impermeants the permeation-limiting channel diameter was obtained: 16 to 20 angstroms for the mammalian cells and 20 to 30 angstroms for the insect cells. |
doi_str_mv | 10.1126/science.7244653 |
format | article |
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From the molecular dimensions of the largest permeants and smallest impermeants the permeation-limiting channel diameter was obtained: 16 to 20 angstroms for the mammalian cells and 20 to 30 angstroms for the insect cells.</abstract><cop>United States</cop><pub>The American Association for the Advancement Science</pub><pmid>7244653</pmid><doi>10.1126/science.7244653</doi><tpages>3</tpages></addata></record> |
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source | American Association for the Advancement of Science; JSTOR Archival Journals and Primary Sources Collection |
subjects | animal cells Animal glands Animals Cell culture techniques Cell interaction Cell interactions cell junctions Cell Line channels Chironomidae Cultured cells DNA Fluorescent Dyes fluorescent probes Giant cells Glycopeptides Glycopeptides - metabolism insects Intercellular junctions Intercellular Junctions - ultrastructure Mice Mice, Inbred BALB C Models, Molecular Molecules Oligosaccharides - metabolism Plasmids Protein Conformation salivary gland Salivary glands Salivary Glands - ultrastructure Species Specificity |
title | Diameter of the Cell-to-Cell Junctional Membrane Channels as Probed with Neutral Molecules |
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