Obstetrical and Neonatal Outcomes of Pregnancies following Gastric Bypass Surgery: A Retrospective Cohort Study in a French Referral Centre

Background The objective of this study was to analyze obstetrical and neonatal outcomes following Roux en Y Gastric Bypass procedures (RYGBP). Methods A retrospective cohort study was conducted in a single French tertiary perinatal care and bariatric center. The study involved 24 pregnancies, follow...

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Bibliographic Details
Published in:Obesity surgery 2010-11, Vol.20 (11), p.1501-1508
Main Authors: Santulli, Pietro, Mandelbrot, Laurent, Facchiano, Enrico, Dussaux, Chloé, Ceccaldi, Pierre-François, Ledoux, Séverine, Msika, Simon
Format: Article
Language:English
Subjects:
Adult
Birth weight
Clinical outcomes
Clinical Research
Cohort Studies
Female
Fetal Growth Retardation - etiology
Gastric Bypass - adverse effects
Gastrointestinal surgery
Humans
Infant, Low Birth Weight
Infant, Newborn
Medicine
Medicine & Public Health
Obesity
Obesity - surgery
Pregnancy
Pregnancy Outcome
Retrospective Studies
Surgery
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Summary:Background The objective of this study was to analyze obstetrical and neonatal outcomes following Roux en Y Gastric Bypass procedures (RYGBP). Methods A retrospective cohort study was conducted in a single French tertiary perinatal care and bariatric center. The study involved 24 pregnancies, following RYGBP (exposed group) and two different control groups (non-exposed groups). A body mass index (BMI)-matched control group included 120 pregnancies matched for age, parity, and pregnancy BMI. A normal BMI control group included 120 pregnancies with normal BMI (18.5–24.9 kg/m 2 ), matched for age and parity. Hospital data were reviewed from all groups in the same 6-year period. Obstetrical and neonatal outcomes after RYGB were compared, separately, to the two different-matched control groups. Results The median interval from RYGBP to conception was 26.6 (range: 3–74) months. Rates of perinatal complications did not differ significantly between the RYGBP group and normal BMI and BMI-matched controls groups. The rate of Cesarean section before labor was higher in the RYGBP patients than in the normal BMI control group (25% vs. 9.3% respectively, p  = 0.04). Weight gain was lower in the RYGBP patients than normal BMI control group (5.8 kg vs. 13.2 kg respectively, p  
ISSN:0960-8923
1708-0428
DOI:10.1007/s11695-010-0260-6