Life expectancy in pediatric patients with cerebral palsy and neuromuscular scoliosis who underwent spinal fusion

The aim of this study was to document the rate of survival among 288 severely affected pediatric patients (154 females, 134 males) with spasticity and neuromuscular scoliosis who underwent spinal fusion (mean age at surgery 13 years 11 months, SD 3 years 4 months), and to identify exposure variables...

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Bibliographic Details
Published in:Developmental medicine and child neurology 2003-10, Vol.45 (10), p.677-682
Main Authors: Tsirikos, Athanasios I, Chang, Wei-Ning, Dabney, Kirk W, Miller, Freeman, Glutting, Joseph
Format: Article
Language:English
Subjects:
Adolescent
Caregivers
Cerebral Palsy
Cerebral Palsy - mortality
Cerebral Palsy - physiopathology
Cerebral Palsy - surgery
Child
Child, Preschool
Cognitive Ability
Cohort Studies
Death
Female
Hospitals
Humans
Infant
Intellectual Disability
Intraoperative Complications
Kyphosis - mortality
Kyphosis - physiopathology
Kyphosis - surgery
Life Expectancy
Male
Neurological Impairments
Neuromuscular Junction - physiopathology
Nutrition
Original Articles
Patients
Physical Disabilities
Preoperative Care
Risk Factors
Scoliosis - mortality
Scoliosis - physiopathology
Scoliosis - surgery
Selection Criteria
Severe Disabilities
Severity of Illness Index
Spinal Fusion - methods
Statistical Analysis
Surgery
Survival Rate
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Summary:The aim of this study was to document the rate of survival among 288 severely affected pediatric patients (154 females, 134 males) with spasticity and neuromuscular scoliosis who underwent spinal fusion (mean age at surgery 13 years 11 months, SD 3 years 4 months), and to identify exposure variables that could significantly predict survival times. Kaplan–Meier survival analysis was performed demonstrating a mean predicted survival of 11 years 2 months after spinal surgery for this group of globally involved children with cerebral palsy (CP). Cox's proportional hazards model was used to evaluate predictive efficacy of exposure variables, such as sex, age at surgery, level of ambulation, cognitive ability, degree of coronal and sagittal plane spinal deformity, intraoperative blood loss, surgical time, days in hospital, and days in the intensive care unit. Number of days in intensive care unit after surgery and the presence of severe preoperative thoracic hyperkyphosis were the only factors affecting survival rates. This demonstrated statistically significant predictability for decreased life expectancy after spinal fusion in children with CP.
ISSN:0012-1622
1469-8749
DOI:10.1017/S0012162203001269