Quantitative analysis of revascularisation and new bone formation in experimental bone grafts : the use of an image input and processing system

Revascularisation and new bone formation in bone grafts has been extensively studied by histological techniques, but the images obtained are very complex and consequently difficult to evaluate quantitatively. We report similar analyses in experimental bone grafts using newer computerised digital tec...

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Bibliographic Details
Published in:International orthopaedics 1993-04, Vol.17 (2), p.109-112
Main Authors: YANO, H, MASUMI, S, FUKUNAGA, T, IKEBE, S
Format: Article
Language:English
Subjects:
Angiography - methods
Animals
Biological and medical sciences
Bone and Bones - blood supply
Bone Development
Bone Transplantation
Medical sciences
Orthopedic surgery
Preservation, Biological
Rabbits
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Time Factors
Transplantation, Autologous
Transplantation, Homologous
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Summary:Revascularisation and new bone formation in bone grafts has been extensively studied by histological techniques, but the images obtained are very complex and consequently difficult to evaluate quantitatively. We report similar analyses in experimental bone grafts using newer computerised digital techniques. Fresh autografts and fresh and frozen allografts were used. The histological analogue images from them were input digitally into an image processor. The amount of revascularisation and new bone formation could then be quantified in the different grafts. This system has proved to be a useful method of evaluation which could be applied to the quantitative analysis of other histological images.
ISSN:0341-2695
1432-5195
DOI:10.1007/BF00183552