Effects of “Moxibustion Serum”on Proliferation and Phenotypes of Tumor Infiltrating Lymphocytes

Tumor infiltrating lymphocytes (TIL) were cultured with “moxibustion serum”(MS), and the results were examined by flow cytometry. The results indicated that MS could enhance the proliferation of TIL,accelerate it to reach the exponential growth phase, and assist recombinant interleukin 2 (rIL-2) to...

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Bibliographic Details
Published in:Journal of traditional Chinese medicine 2003-09, Vol.23 (3), p.225-229
Main Author: 陈云飞 赵粹英 陈汉平 秦慧莲 方航
Format: Article
Language:English
Subjects:
Animals
Artemisia
Biological and medical sciences
Blood
CD3 Complex - immunology
CD4-CD8 Ratio
Cell Division - drug effects
Culture Media, Conditioned
Drugs, Chinese Herbal - pharmacology
Female
Interleukin-2 - immunology
Lymphocytes, Tumor-Infiltrating - cytology
Medical sciences
Mice
Mice, Inbred C57BL
Miscellaneous
Moxibustion
Phenotype
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Recombinant Proteins - immunology
Thymus Neoplasms - pathology
Tropical medicine
Tumor Cells, Cultured
淋巴细胞
细胞增殖
艾灸血清
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Summary:Tumor infiltrating lymphocytes (TIL) were cultured with “moxibustion serum”(MS), and the results were examined by flow cytometry. The results indicated that MS could enhance the proliferation of TIL,accelerate it to reach the exponential growth phase, and assist recombinant interleukin 2 (rIL-2) to enhance successively the percentage of CD3^+ positive cells, maintain the number of CD4^+ positive T cells, promote greatly the percentage of CD8^+ positive T cells among TILs, and reverse the CD4^+/CD8^+ ratio. Such cooperative effects rely on relative specificity of acupoints. It is suggested that MS is beneficial to the growth of TIL both in the aspects of proliferation and phenotypes.
ISSN:0255-2922