Plasma levels of cortisol and corticosteroid-binding globulin (CBG) and hepatic CBG mRNA expression in pre- and postnatal pigs

The relationships among hepatic corticosteroid-binding globulin (CBG) mRNA expression and plasma concentrations of cortisol and CBG was evaluated in fetal pigs ( n=7–14 per age) on days 50, 70, 80, 90, and 104 of gestation and postnatal pigs ( n=8 per age) on days 1, 3, 10, 20, 30, and 40 following...

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Bibliographic Details
Published in:Domestic animal endocrinology 2003-10, Vol.25 (3), p.263-273
Main Authors: Heo, Jeonghoon, Kattesh, Henry G, Roberts, Mary P, Schneider, John F
Format: Article
Language:English
Subjects:
Aging - blood
Animals
bioavailability
CBG
CBG mRNA
Cortisol
Female
Fetal Blood - metabolism
gene expression
Gene Expression Regulation, Developmental
Hydrocortisone - blood
Liver - embryology
Liver - metabolism
messenger RNA
postnatal development
Pre- and postnatal pigs
Pregnancy
prenatal development
Radioimmunoassay - veterinary
Random Allocation
RNA, Messenger - analysis
swine
Swine - blood
Swine - embryology
Transcortin - genetics
Transcortin - metabolism
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Summary:The relationships among hepatic corticosteroid-binding globulin (CBG) mRNA expression and plasma concentrations of cortisol and CBG was evaluated in fetal pigs ( n=7–14 per age) on days 50, 70, 80, 90, and 104 of gestation and postnatal pigs ( n=8 per age) on days 1, 3, 10, 20, 30, and 40 following birth. In fetal pigs, hepatic CBG mRNA expression was highest ( P
ISSN:0739-7240
1879-0054
DOI:10.1016/S0739-7240(03)00055-9