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Nephrogenic diabetes insipidus in sibling colts
Nephrogenic diabetes insipidus was diagnosed in two full sibling Thoroughbred colts. Each colt had a history of excessive urination. Extreme polydipsia (greater than 80 L per day) was documented in both colts. Inability to concentrate urine in response to water deprivation, infusion of hypertonic sa...
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| Published in: | Journal of veterinary internal medicine 1993-03, Vol.7 (2), p.68-72 |
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| Language: | English |
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| container_end_page | 72 |
| container_issue | 2 |
| container_start_page | 68 |
| container_title | Journal of veterinary internal medicine |
| container_volume | 7 |
| creator | Schott, H.C. II Bayley, W.M Reed, S.M Brobst, D.F |
| description | Nephrogenic diabetes insipidus was diagnosed in two full sibling Thoroughbred colts. Each colt had a history of excessive urination. Extreme polydipsia (greater than 80 L per day) was documented in both colts. Inability to concentrate urine in response to water deprivation, infusion of hypertonic saline, or exogenous vasopressin administration indicated insensitivity of the collecting duct epithelial cells to vasopressin. A diagnosis of nephrogenic diabetes insipidus was further supported by a normal increase in plasma vasopressin concentration after water deprivation in the one colt in which such testing was pursued. |
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II ; Bayley, W.M ; Reed, S.M ; Brobst, D.F</creator><creatorcontrib>Schott, H.C. II ; Bayley, W.M ; Reed, S.M ; Brobst, D.F</creatorcontrib><description>Nephrogenic diabetes insipidus was diagnosed in two full sibling Thoroughbred colts. Each colt had a history of excessive urination. Extreme polydipsia (greater than 80 L per day) was documented in both colts. Inability to concentrate urine in response to water deprivation, infusion of hypertonic saline, or exogenous vasopressin administration indicated insensitivity of the collecting duct epithelial cells to vasopressin. A diagnosis of nephrogenic diabetes insipidus was further supported by a normal increase in plasma vasopressin concentration after water deprivation in the one colt in which such testing was pursued.</description><identifier>ISSN: 0891-6640</identifier><identifier>EISSN: 1939-1676</identifier><identifier>PMID: 8501698</identifier><language>eng</language><publisher>United States</publisher><subject>Animals ; CABALLOS ; CHEVAL ; DIABETE ; DIABETES ; Diabetes Insipidus - genetics ; Diabetes Insipidus - urine ; Diabetes Insipidus - veterinary ; FOALS ; FRATRIE ; FUNCTIONAL DISORDERS ; GENE RECESSIF ; GENES RECESIVOS ; GENETICA ; GENETICS ; GENETIQUE ; HERMANOS ; Horse Diseases - genetics ; Horse Diseases - urine ; HORSES ; Kidney Concentrating Ability ; Kidney Diseases - genetics ; Kidney Diseases - urine ; Kidney Diseases - veterinary ; Male ; POLYDIPSIA ; POLYURIA ; POTRO ; POULAIN ; RECESSIVE GENES ; SEX ; SEX LINKAGE ; SEXE ; SEXO ; SIBLINGS ; SINTOMAS ; SYMPTOME ; SYMPTOMS ; TRASTORNOS DE LA ORINA ; TRASTORNOS FUNCIONALES ; TROUBLE FONCTIONNEL ; TROUBLE URINAIRE ; URINATION DISORDERS ; Vasopressins</subject><ispartof>Journal of veterinary internal medicine, 1993-03, Vol.7 (2), p.68-72</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8501698$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schott, H.C. II</creatorcontrib><creatorcontrib>Bayley, W.M</creatorcontrib><creatorcontrib>Reed, S.M</creatorcontrib><creatorcontrib>Brobst, D.F</creatorcontrib><title>Nephrogenic diabetes insipidus in sibling colts</title><title>Journal of veterinary internal medicine</title><addtitle>J Vet Intern Med</addtitle><description>Nephrogenic diabetes insipidus was diagnosed in two full sibling Thoroughbred colts. Each colt had a history of excessive urination. Extreme polydipsia (greater than 80 L per day) was documented in both colts. Inability to concentrate urine in response to water deprivation, infusion of hypertonic saline, or exogenous vasopressin administration indicated insensitivity of the collecting duct epithelial cells to vasopressin. A diagnosis of nephrogenic diabetes insipidus was further supported by a normal increase in plasma vasopressin concentration after water deprivation in the one colt in which such testing was pursued.</description><subject>Animals</subject><subject>CABALLOS</subject><subject>CHEVAL</subject><subject>DIABETE</subject><subject>DIABETES</subject><subject>Diabetes Insipidus - genetics</subject><subject>Diabetes Insipidus - urine</subject><subject>Diabetes Insipidus - veterinary</subject><subject>FOALS</subject><subject>FRATRIE</subject><subject>FUNCTIONAL DISORDERS</subject><subject>GENE RECESSIF</subject><subject>GENES RECESIVOS</subject><subject>GENETICA</subject><subject>GENETICS</subject><subject>GENETIQUE</subject><subject>HERMANOS</subject><subject>Horse Diseases - genetics</subject><subject>Horse Diseases - urine</subject><subject>HORSES</subject><subject>Kidney Concentrating Ability</subject><subject>Kidney Diseases - genetics</subject><subject>Kidney Diseases - urine</subject><subject>Kidney Diseases - veterinary</subject><subject>Male</subject><subject>POLYDIPSIA</subject><subject>POLYURIA</subject><subject>POTRO</subject><subject>POULAIN</subject><subject>RECESSIVE GENES</subject><subject>SEX</subject><subject>SEX LINKAGE</subject><subject>SEXE</subject><subject>SEXO</subject><subject>SIBLINGS</subject><subject>SINTOMAS</subject><subject>SYMPTOME</subject><subject>SYMPTOMS</subject><subject>TRASTORNOS DE LA ORINA</subject><subject>TRASTORNOS FUNCIONALES</subject><subject>TROUBLE FONCTIONNEL</subject><subject>TROUBLE URINAIRE</subject><subject>URINATION DISORDERS</subject><subject>Vasopressins</subject><issn>0891-6640</issn><issn>1939-1676</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><recordid>eNotT0tLxEAYG0RZ6-ofEISevBXnPf2OsugqLHrQPZd51pG-7LQH_72V7SUJJCTkDGUEGBREKnmOMlwCKaTk-BJdpfSNMRVCqA3alAITCWWGHt788DX2te-izV3Uxk8-5bFLcYhu_ld5iqaJXZ3bvpnSNboIukn-ZuUtOj4_fe5eisP7_nX3eCgCpWIquKGGAaHYcKMc1lI4AYEvaBWB4CxVYKzyWAfudGlBM5BhWddUESks26L7U-8w9j-zT1PVxmR90-jO93OqlFCSlIwtwbs1OJvWu2oYY6vH32p9uPi3Jz_ovtL1GFN1_ADOFWDC_gCT1FXT</recordid><startdate>199303</startdate><enddate>199303</enddate><creator>Schott, H.C. II</creator><creator>Bayley, W.M</creator><creator>Reed, S.M</creator><creator>Brobst, D.F</creator><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>199303</creationdate><title>Nephrogenic diabetes insipidus in sibling colts</title><author>Schott, H.C. II ; Bayley, W.M ; Reed, S.M ; Brobst, D.F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-f225t-4b2b39120b4b7d0a65d59f45d5c719fdc279bc7e0af4da8c9a396fabea27165c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Animals</topic><topic>CABALLOS</topic><topic>CHEVAL</topic><topic>DIABETE</topic><topic>DIABETES</topic><topic>Diabetes Insipidus - genetics</topic><topic>Diabetes Insipidus - urine</topic><topic>Diabetes Insipidus - veterinary</topic><topic>FOALS</topic><topic>FRATRIE</topic><topic>FUNCTIONAL DISORDERS</topic><topic>GENE RECESSIF</topic><topic>GENES RECESIVOS</topic><topic>GENETICA</topic><topic>GENETICS</topic><topic>GENETIQUE</topic><topic>HERMANOS</topic><topic>Horse Diseases - genetics</topic><topic>Horse Diseases - urine</topic><topic>HORSES</topic><topic>Kidney Concentrating Ability</topic><topic>Kidney Diseases - genetics</topic><topic>Kidney Diseases - urine</topic><topic>Kidney Diseases - veterinary</topic><topic>Male</topic><topic>POLYDIPSIA</topic><topic>POLYURIA</topic><topic>POTRO</topic><topic>POULAIN</topic><topic>RECESSIVE GENES</topic><topic>SEX</topic><topic>SEX LINKAGE</topic><topic>SEXE</topic><topic>SEXO</topic><topic>SIBLINGS</topic><topic>SINTOMAS</topic><topic>SYMPTOME</topic><topic>SYMPTOMS</topic><topic>TRASTORNOS DE LA ORINA</topic><topic>TRASTORNOS FUNCIONALES</topic><topic>TROUBLE FONCTIONNEL</topic><topic>TROUBLE URINAIRE</topic><topic>URINATION DISORDERS</topic><topic>Vasopressins</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schott, H.C. II</creatorcontrib><creatorcontrib>Bayley, W.M</creatorcontrib><creatorcontrib>Reed, S.M</creatorcontrib><creatorcontrib>Brobst, D.F</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of veterinary internal medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schott, H.C. II</au><au>Bayley, W.M</au><au>Reed, S.M</au><au>Brobst, D.F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nephrogenic diabetes insipidus in sibling colts</atitle><jtitle>Journal of veterinary internal medicine</jtitle><addtitle>J Vet Intern Med</addtitle><date>1993-03</date><risdate>1993</risdate><volume>7</volume><issue>2</issue><spage>68</spage><epage>72</epage><pages>68-72</pages><issn>0891-6640</issn><eissn>1939-1676</eissn><abstract>Nephrogenic diabetes insipidus was diagnosed in two full sibling Thoroughbred colts. Each colt had a history of excessive urination. Extreme polydipsia (greater than 80 L per day) was documented in both colts. Inability to concentrate urine in response to water deprivation, infusion of hypertonic saline, or exogenous vasopressin administration indicated insensitivity of the collecting duct epithelial cells to vasopressin. A diagnosis of nephrogenic diabetes insipidus was further supported by a normal increase in plasma vasopressin concentration after water deprivation in the one colt in which such testing was pursued.</abstract><cop>United States</cop><pmid>8501698</pmid><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0891-6640 |
| ispartof | Journal of veterinary internal medicine, 1993-03, Vol.7 (2), p.68-72 |
| issn | 0891-6640 1939-1676 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75761833 |
| source | Wiley Open Access |
| subjects | Animals CABALLOS CHEVAL DIABETE DIABETES Diabetes Insipidus - genetics Diabetes Insipidus - urine Diabetes Insipidus - veterinary FOALS FRATRIE FUNCTIONAL DISORDERS GENE RECESSIF GENES RECESIVOS GENETICA GENETICS GENETIQUE HERMANOS Horse Diseases - genetics Horse Diseases - urine HORSES Kidney Concentrating Ability Kidney Diseases - genetics Kidney Diseases - urine Kidney Diseases - veterinary Male POLYDIPSIA POLYURIA POTRO POULAIN RECESSIVE GENES SEX SEX LINKAGE SEXE SEXO SIBLINGS SINTOMAS SYMPTOME SYMPTOMS TRASTORNOS DE LA ORINA TRASTORNOS FUNCIONALES TROUBLE FONCTIONNEL TROUBLE URINAIRE URINATION DISORDERS Vasopressins |
| title | Nephrogenic diabetes insipidus in sibling colts |
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