Delivery outcome of women with epilepsy:a population‐based cohort study

• Published in: BJOG : an international journal of obstetrics and gynaecology 2010-11, Vol.117 (12), p.1537-1543
• Main Authors: Borthen, I, Eide, MG, Daltveit, AK, Gilhus, NE
• Format: Article
• Language: English
• Subjects: Adult; Anticonvulsants - adverse effects; Biological and medical sciences; Birth Weight; Caesarean delivery; Cesarean Section; Childbirth & labor; Cohort Studies; delivery; Delivery. Postpartum. Lactation; Drug therapy; Epilepsy; Epilepsy - drug therapy; Female; Gynecology. Andrology. Obstetrics; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy; Humans; Infant, Newborn; Medical sciences; Nervous system (semeiology, syndromes); Neurology; Norway; obstetric outcome; postpartum haemorrhage; Postpartum Hemorrhage - chemically induced; Pregnancy; Pregnancy Complications - drug therapy; Pregnancy Outcome; Risk Factors
• ISSN: 1470-0328; 1471-0528
• DOI: 10.1111/j.1471-0528.2010.02694.x

Please cite this paper as: Borthen I, Eide M, Daltveit A, Gilhus N. Delivery outcome of women with epilepsy: a population‐based cohort study.
BJOG 2010;117:1537–1543. Objective  To investigate whether women with epilepsy have increased risks of complications during labour, and to explore the impact of antiepileptic drug use. Design  Population‐based cohort study. Setting  Data from the Medical Birth Registry of Norway 1999–2005. Population  All births (n = 372 128) delivered in Norway, ensured through linkage with the National Population Registry run by Statistics Norway. All singleton births and the first child in multiple pregnancies were included, leaving 365 107 pregnancies for analysis. Methods  Data from the Medical Birth Registry of Norway 1999–2005 were analysed. Main outcome measures  Induction, caesarean section, use of forceps and vacuum, abnormal presentation, placental abruption, mechanical disproportion, postpartum haemorrhage, atony and Apgar score