Mortality and bloodstream infections in geriatrics units

Abstract The purpose of this retrospective study was to evaluate risk factors of mortality in bloodstream infections in old and very old people in a French geriatric unit (Paul Brousse Hospital, APHP). 167 older patients with bloodstream infections were included and two groups were compared accordin...

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Bibliographic Details
Published in:Archives of gerontology and geriatrics 2010-11, Vol.51 (3), p.e106-e109
Main Authors: Burlaud, Aurore, Mathieu, Danièle, Falissard, Bruno, Trivalle, Christophe
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Albumins - metabolism
Bacteremia - mortality
Bacteremia in elderly
C-Reactive Protein - metabolism
Chi-Square Distribution
Cross Infection - mortality
Female
Fever - complications
France - epidemiology
Humans
Internal Medicine
Logistic Models
Male
Malnutrition
Malnutrition - complications
Middle Aged
Mortality
Retrospective Studies
Risk Factors
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Summary:Abstract The purpose of this retrospective study was to evaluate risk factors of mortality in bloodstream infections in old and very old people in a French geriatric unit (Paul Brousse Hospital, APHP). 167 older patients with bloodstream infections were included and two groups were compared according to age (60–85 years and ≥85 years). Information was collected for each patient: age, sex, diseases, urinary catheter, temperature, signs of severe sepsis, biological examinations, bacteria and antibiotic treatments. All bacteremias were nosocomial. There was no difference between groups for pathogen, source or prognosis. Mortality rate at 60 days was 32.3%. The risk factors for mortality were: low albumin rate ( p < 0.001), high C-reactive protein (CRP) ( p = 0.02) and moderate fever ( p = 0.006). Multivariate logistic regression showed that these three parameters were significantly associated with a risk of mortality. The parameter with the highest risk was a low albumin rate
ISSN:0167-4943
1872-6976
DOI:10.1016/j.archger.2010.01.012