Successful Treatment of Simultaneous Pulmonary Pseudallescheria boydii and Aspergillus terreus Infection with Oral Itraconazole

Pseudallescheria boydii and Aspergillus terreus are unusual opportunistic fungal pathogens that are often resistant to chemotherapy with amphotericin B. We report a case of simultaneous invasive pulmonary infection with these organisms occurring in a bone marrow transplant recipient who was successf...

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Bibliographic Details
Published in:Clinical infectious diseases 1993-06, Vol.16 (6), p.803-805
Main Authors: Goldberg, Stuart L., Geha, Daniel J., Marshall, William F., Inwards, David J., Hoagland, H. Clark
Format: Article
Language:English
Subjects:
Administration, Oral
Adult
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antifungal agents
Antifungal Agents - administration & dosage
Antifungal Agents - therapeutic use
Antifungals
Aspergillosis - drug therapy
Aspergillosis - etiology
Aspergillosis - surgery
Aspergillus
Aspergillus - drug effects
Aspergillus terreus
Biological and medical sciences
Bone Marrow Transplantation - adverse effects
Bone Marrow Transplantation - immunology
Debridement
Fungal diseases
Fungal infections
Graft vs Host Disease - complications
Graft vs Host Disease - etiology
Humans
Immunocompromised Host
Immunosuppressants
Infections
Itraconazole
Ketoconazole - administration & dosage
Ketoconazole - analogs & derivatives
Ketoconazole - pharmacology
Ketoconazole - therapeutic use
Lesions
Lung - diagnostic imaging
Lung - microbiology
Lung diseases
Lung Diseases, Fungal - drug therapy
Lung Diseases, Fungal - etiology
Lung Diseases, Fungal - surgery
Male
Medical sciences
Microbial Sensitivity Tests
Mycetoma - drug therapy
Mycetoma - etiology
Mycetoma - surgery
Opportunistic Infections - drug therapy
Opportunistic Infections - etiology
Opportunistic Infections - surgery
Pharmacology. Drug treatments
Pseudallescheria
Pseudallescheria - drug effects
Pseudallescheria boydii
Tomography, X-Ray Computed
Transplantation
Transplantation, Autologous
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Description
Summary:Pseudallescheria boydii and Aspergillus terreus are unusual opportunistic fungal pathogens that are often resistant to chemotherapy with amphotericin B. We report a case of simultaneous invasive pulmonary infection with these organisms occurring in a bone marrow transplant recipient who was successfully treated with the oral azole itraconazole.
ISSN:1058-4838
1537-6591
DOI:10.1093/clind/16.6.803