The Role of Thallium Scintigraphy in Excluding Malignancy in Bone

Scintigraphy with thallium-201 was performed on 22 patients in whom a solitary abnormality in bone was suspected of being malignant. In three patients, an additional lesion was subsequently identified. Preferential TI-201 uptake was found in 7 of B malignant lesions, but was absent in 16 of 17 abnor...

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Bibliographic Details
Published in:Clinical nuclear medicine 1993-07, Vol.18 (7), p.551-557
Main Authors: DER WALL, HANS VAN, C. MURRAY, I PROVAN, HUCKSTER, RON L, PHILIPS, ROBERT L
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Biological and medical sciences
Bone Diseases - diagnostic imaging
Bone Diseases - pathology
Bone Neoplasms - diagnostic imaging
Bone Neoplasms - pathology
Child
Female
Humans
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Middle Aged
Osteoarticular system. Muscles
Radionuclide Imaging
Radionuclide investigations
Thallium Radioisotopes
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Description
Summary:Scintigraphy with thallium-201 was performed on 22 patients in whom a solitary abnormality in bone was suspected of being malignant. In three patients, an additional lesion was subsequently identified. Preferential TI-201 uptake was found in 7 of B malignant lesions, but was absent in 16 of 17 abnormalities that proved to be benign. The use of TI-201 scanning is considered to offer high negative predictive value in the assessment of possible malignant change in bone.
ISSN:0363-9762
1536-0229
DOI:10.1097/00003072-199307000-00001