Dorsal bundle lesions do not affect latent inhibition of conditioned suppression

Three experiments are reported which examine the effects of lesions of the dorsal ascending noradrenergic bundle (DB) on latent inhibition using a conditioned suppression procedure in rats. In none of the experiments did the DB lesion have any effect, despite changes in the extent of latent inhibiti...

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Bibliographic Details
Published in:Psychopharmacologia 1984-01, Vol.84 (4), p.549-555
Main Authors: TSALTAS, E, PRESTON, G. C, RAWLINS, J. N. P, WINOCUR, G, GRAY, J. A
Format: Article
Language:English
Subjects:
Animals
Behavioral psychophysiology
Biological and medical sciences
Conditioning, Operant - physiology
Fundamental and applied biological sciences. Psychology
Hydroxydopamines - pharmacology
Hypothalamus - physiology
Male
Neural Inhibition
Neural Pathways - physiology
Norepinephrine - physiology
Oxidopamine
Psychology. Psychoanalysis. Psychiatry
Psychology. Psychophysiology
Rats
Rats, Inbred Strains
Reaction Time
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Summary:Three experiments are reported which examine the effects of lesions of the dorsal ascending noradrenergic bundle (DB) on latent inhibition using a conditioned suppression procedure in rats. In none of the experiments did the DB lesion have any effect, despite changes in the extent of latent inhibition and in the control procedures used to assess it. The results are discussed in relation to the attentional theory of DB function.
ISSN:0033-3158
1432-2072
DOI:10.1007/BF00431465