Fabrication and biocompatibility investigation of TiO2 films on the polymer substrates obtained via a novel and versatile route

Titanium oxide (TiO2) films were successfully deposited onto the polymer substrates of polytetrafluoroethylene (PTFE), polyethylene (PE), and polyethylene terephthalate (PET), which were pre-modified with polydopamine coating (polydopamine and its coating are coded as PDA and PDAc, respectively), by...

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Bibliographic Details
Published in:Colloids and surfaces, B, Biointerfaces B, Biointerfaces, 2010-03, Vol.76 (1), p.123-127
Main Authors: Ou, Junfei, Wang, Jinqing, Zhang, Dong, Zhang, Puliang, Liu, Sheng, Yan, Penghua, Liu, Bin, Yang, Shengrong
Format: Article
Language:English
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Summary:Titanium oxide (TiO2) films were successfully deposited onto the polymer substrates of polytetrafluoroethylene (PTFE), polyethylene (PE), and polyethylene terephthalate (PET), which were pre-modified with polydopamine coating (polydopamine and its coating are coded as PDA and PDAc, respectively), by a simple liquid phase deposition (LPD) process. The morphology and chemical state of the obtained TiO2 films were characterized by field emission scanning electron microscope (FE-SEM) and X-ray photoelectron spectroscopy (XPS), respectively. Subsequently, the biocompatibility of the samples was investigated by 3-(4,5-dimethyldiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) colorimetric assay and acridine orange staining of MC-3T3 osteoblast cells, and the results demonstrated that the fabricated TiO2 films could markedly improve the in vitro cytocompatibility. So, the presented route is anticipated to be a promising surface modification methodology to improve the practical outcome of the implanted materials for its versatility and validity.
ISSN:0927-7765
DOI:10.1016/j.colsurfb.2009.10.024