Cortical mapping by functional magnetic resonance imaging in patients with brain tumors

The aim of our study was to establish the effectiveness of the functional MRI (fMRI) technique in comparison with intraoperative cortical stimulation (ICS) in planning cortex-saving neurosurgical interventions. The combination of sensory and motor stimulation during fMRI experiments was used to impr...

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Bibliographic Details
Published in:European radiology 2005-06, Vol.15 (6), p.1148-1158
Main Authors: Majos, Agata, Tybor, Krzysztof, Stefańczyk, Ludomir, Góraj, Bozena
Format: Article
Language:English
Subjects:
Adult
Aged
Agreements
Brain
Brain cancer
Brain mapping
Brain Mapping - methods
Brain Neoplasms - physiopathology
Brain Neoplasms - surgery
Brain tumors
Case-Control Studies
Cortex (motor)
Female
Functional magnetic resonance imaging
Humans
Linear Models
Localization
Magnetic resonance imaging
Magnetic Resonance Imaging - methods
Male
Mapping
Middle Aged
Motor Cortex - physiopathology
Neuroimaging
Neurosurgery
Somatosensory cortex
Somatosensory Cortex - physiopathology
Stimulation
Structure-function relationships
Tumors
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Summary:The aim of our study was to establish the effectiveness of the functional MRI (fMRI) technique in comparison with intraoperative cortical stimulation (ICS) in planning cortex-saving neurosurgical interventions. The combination of sensory and motor stimulation during fMRI experiments was used to improve the exactness of central sulcus localization. The study subjects were 30 volunteers and 33 patients with brain tumors in the rolandic area. Detailed topographical relations of activated areas in fMRI and intraoperative techniques were compared. The agreement in the location defined by the two methods for motor centers was found to be 84%; for sensory centers it was 83%. When both kinds of activation are taken into account this agreement increases to 98%. A significant relation was found between fMRI and ICS for the agreement of the distance both for motor and sensory centers (p=0.0021-0.0024). Also a strong dependence was found between the agreement of the location and the agreement of the distance for both kinds of stimulation. The spatial correlation between fMRI and ICS methods for the sensorimotor cortex is very high. fMRI combining functional and structural information is very helpful for preoperative neurosurgical planning. The sensitivity of the fMRI technique in brain mapping increases when using both motor and sensory paradigms in the same patient.
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-004-2565-0