Fatal Pneumocystis pneumonia in a child treated for focal segmental glomerulosclerosis

A 4-year-old female with nephrotic syndrome secondary to focal segmental glomerulosclerosis (FSGS) was treated with pulse methylprednisolone and chlorambucil therapy. She subsequently developed fatal Pneumocystis carinii pneumonia (PCP). This is the first report of a pediatric patient whose treatmen...

Full description

Saved in:
Bibliographic Details
Published in:Pediatric nephrology (Berlin, West) West), 1993-08, Vol.7 (4), p.444-445
Main Authors: MURPHY, J. L, KANO, H. L, CHENAILLE, P. J, MAKKER, S. P
Format: Article
Language:English
Subjects:
Biological and medical sciences
Child, Preschool
Chlorambucil - therapeutic use
Drug toxicity and drugs side effects treatment
Fatal Outcome
Female
Glomerulosclerosis, Focal Segmental - complications
Glomerulosclerosis, Focal Segmental - drug therapy
Humans
Medical sciences
Methylprednisolone - therapeutic use
Opportunistic Infections - etiology
Pharmacology. Drug treatments
Pneumonia, Pneumocystis - etiology
Toxicity: blood
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A 4-year-old female with nephrotic syndrome secondary to focal segmental glomerulosclerosis (FSGS) was treated with pulse methylprednisolone and chlorambucil therapy. She subsequently developed fatal Pneumocystis carinii pneumonia (PCP). This is the first report of a pediatric patient whose treatment for FSGS resulted in PCP, raising the issue of PCP prophylaxis for these patients.
ISSN:0931-041X
1432-198X
DOI:10.1007/BF00857565