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Fatal Pneumocystis pneumonia in a child treated for focal segmental glomerulosclerosis

A 4-year-old female with nephrotic syndrome secondary to focal segmental glomerulosclerosis (FSGS) was treated with pulse methylprednisolone and chlorambucil therapy. She subsequently developed fatal Pneumocystis carinii pneumonia (PCP). This is the first report of a pediatric patient whose treatmen...

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Published in:Pediatric nephrology (Berlin, West) West), 1993-08, Vol.7 (4), p.444-445
Main Authors: MURPHY, J. L, KANO, H. L, CHENAILLE, P. J, MAKKER, S. P
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KANO, H. L
CHENAILLE, P. J
MAKKER, S. P
description A 4-year-old female with nephrotic syndrome secondary to focal segmental glomerulosclerosis (FSGS) was treated with pulse methylprednisolone and chlorambucil therapy. She subsequently developed fatal Pneumocystis carinii pneumonia (PCP). This is the first report of a pediatric patient whose treatment for FSGS resulted in PCP, raising the issue of PCP prophylaxis for these patients.
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subjects Biological and medical sciences
Child, Preschool
Chlorambucil - therapeutic use
Drug toxicity and drugs side effects treatment
Fatal Outcome
Female
Glomerulosclerosis, Focal Segmental - complications
Glomerulosclerosis, Focal Segmental - drug therapy
Humans
Medical sciences
Methylprednisolone - therapeutic use
Opportunistic Infections - etiology
Pharmacology. Drug treatments
Pneumonia, Pneumocystis - etiology
Toxicity: blood
title Fatal Pneumocystis pneumonia in a child treated for focal segmental glomerulosclerosis
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