The neurosurgical management of brain metastasis from colorectal cancer: a report of three cases

We report herein three cases of brain metastasis from primary colorectal cancer in which the metastatic lesion was resected to effectively relieve neurological symptoms. Case 1 was a 61-year-old woman with a solitary brain metastasis from colorectal cancer and no other metastases; case 2 was a 59-ye...

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Bibliographic Details
Published in:Surgery today (Tokyo, Japan) Japan), 1993-07, Vol.23 (7), p.639-643
Main Authors: Sato, H, Tsuchiya, A, Nomizu, T, Andoh, Y, Nihei, M, Yoshida, T, Abe, R
Format: Article
Language:English
Subjects:
Adenocarcinoma - diagnosis
Adenocarcinoma - secondary
Adenocarcinoma - surgery
Aged
Brain Neoplasms - diagnosis
Brain Neoplasms - secondary
Brain Neoplasms - surgery
Colorectal Neoplasms - pathology
Female
Humans
Middle Aged
Tomography, X-Ray Computed
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Summary:We report herein three cases of brain metastasis from primary colorectal cancer in which the metastatic lesion was resected to effectively relieve neurological symptoms. Case 1 was a 61-year-old woman with a solitary brain metastasis from colorectal cancer and no other metastases; case 2 was a 59-year-old woman who died from liver metastasis 11 months after resection of the metastatic brain tumor; and case 3 was a 68-year-old woman with multiple metastases to the lungs and bones detected before the brain metastasis. According to 16 cases previously reported in the Japanese literature and our 3 cases, the interval between diagnosis of the primary cancer and discovery of brain metastasis was 23 months on average, while the median survival after the discovery of brain metastasis was 7 months. Brain metastases with liver and lung metastases were seen more frequently than brain metastases alone. In these three cases, chemotherapy appears to have been of no use in preventing recurrence. Thus, we believe neurosurgical management to be appropriate for a solitary lesion and that it should be actively pursued to prolong survival and improve quality of life.
ISSN:0941-1291
1436-2813
DOI:10.1007/bf00311915