RESPIRATORY SINUS ARRHYTHMIA: A NEW, OBJECTIVE SEDATION SCORE

We tested if microcomputer-based measurements of heart rate variability and respiratory sinus arrhythmia (RSA) could be used as the basis of an objective sedation score. Measurements were obtained in eight ICU patients before, during and after physiotherapy. Patients were sedated with propofol and a...

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Bibliographic Details
Published in:British journal of anaesthesia : BJA 1993-09, Vol.71 (3), p.354-358
Main Authors: WANG, D.Y., POMFRETT, C.J.D., HEALY, T.E.J.
Format: Article
Language:English
Subjects:
Adult
Aged
Alfentanil - pharmacology
Anesthesia
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Arrhythmia, Sinus - physiopathology
Biological and medical sciences
Critical Care
Female
Heart Rate - physiology
Heart: respiratory sinus arrhythmia
Humans
Local anesthesia. Pain (treatment)
Male
Measurement techniques: heart rate variability
Measurement techniques: heart rate variability, sedation
Medical sciences
Microcomputers
Middle Aged
Monitoring, Physiologic
Physical Therapy Modalities
Propofol - pharmacology
Respiration - physiology
sedation
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Summary:We tested if microcomputer-based measurements of heart rate variability and respiratory sinus arrhythmia (RSA) could be used as the basis of an objective sedation score. Measurements were obtained in eight ICU patients before, during and after physiotherapy. Patients were sedated with propofol and alfentanil and paralysed with atracurium. Mean ECG R-R interval showed little variation, changing from 646.15 (SD 203.15) ms to 596.08 (181.75) ms and 633.98 (184.53) ms before, during and after physiotherapy, respectively (not significant). However, the degree of respiratory sinus arrhythmia, determined using circular statistical analysis, increased significantly, from 0.14 (0.11) to 0.24 (0. 15), during physiotherapy and returned to control after physiotherapy (P < 0.05). Changes in respiratory sinus arrhythmia may provide an objective measurement of sedation in ICU patients and could form the basis of a simple sedation scoring system.
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/71.3.354