Extragenital Mycoplasma hominis Infections in Adults: Emphasis on Immunosuppression

Mycoplasma hominis, a commensal organism that is potentially pathogenic both in maternal perinatal and in neonatal infections, also causes nongenitourinary infections in adults. We reviewed the clinical features of cases from the literature and emphasized recent cases. Infection sites were classifie...

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Bibliographic Details
Published in:Clinical infectious diseases 1993-08, Vol.17 (Supplement-1), p.S243-S249
Main Authors: Meyer, Richard D., Clough, Wendy
Format: Article
Language:English
Subjects:
Adult
Agammaglobulinemia
Agammaglobulinemia - complications
Antibodies
Bacteremia - etiology
Biological and medical sciences
Blood
Central Nervous System Diseases - etiology
Corticosteroids
Cyclosporins
Female
HIV Infection, AIDS, and Mycoplasmal Infection in Immunocompromised Hosts
Humans
Immune Tolerance
Immunodeficiencies
Immunodeficiencies. Immunoglobulinopathies
Immunopathology
Immunosuppression
Infections
Joint Diseases - etiology
Male
Medical sciences
Mycoplasma
Mycoplasma hominis
Mycoplasma Infections - etiology
Mycoplasma Infections - immunology
Respiratory Tract Infections - etiology
Vascular Diseases - etiology
Wound Infection - etiology
Wound infections
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Summary:Mycoplasma hominis, a commensal organism that is potentially pathogenic both in maternal perinatal and in neonatal infections, also causes nongenitourinary infections in adults. We reviewed the clinical features of cases from the literature and emphasized recent cases. Infection sites were classified as blood, vascular sites, wounds, central nervous system, joints, and respiratory tract. Twenty-one of 31 newly summarized cases and 32 of 67 overall cases were associated with immunosuppression and/or hypogammaglobulinemia. Clinical suspicion, use of appropriate culture media, and determinations of γ-globulin levels and of antibodies specific to Mycoplasma are indicated in the proper clinical setting. These types of M. hominis infection appear to be linked to suppressed cell-mediated immunity and/or hypogammaglobulinemia.
ISSN:1058-4838
1537-6591
DOI:10.1093/clinids/17.Supplement_1.S243