Immunocytoma of the skin simulating lymphadenosis benigna cutis

We report a case of primary cutaneous lymphoma, of the lymphoplasmacytoid type (immunocytoma), in which a small neoplastic component was obscured by a dominating reaction exhibiting characteristic features of lymphadenosis benigna cutis. This abnormal cell population was identified because of the un...

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Bibliographic Details
Published in:Archives of dermatological research 1985, Vol.277 (1), p.36-43
Main Authors: VAN DER PUTTE, S. C. J, TOONSTRA, J, SCHUURMAN, H. J, VAN UNNIK, J. A. M
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Diagnosis, Differential
Hematologic and hematopoietic diseases
Humans
Immunoglobulin lambda-Chains - biosynthesis
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Lymphatic Diseases - diagnosis
Lymphoma - diagnosis
Lymphoma - immunology
Lymphoma - pathology
Male
Medical sciences
Plasma Cells - immunology
Skin Diseases - diagnosis
Skin Neoplasms - diagnosis
Skin Neoplasms - immunology
Skin Neoplasms - pathology
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Summary:We report a case of primary cutaneous lymphoma, of the lymphoplasmacytoid type (immunocytoma), in which a small neoplastic component was obscured by a dominating reaction exhibiting characteristic features of lymphadenosis benigna cutis. This abnormal cell population was identified because of the unusual cytomorphology of the tumor cells, which showed deeply indented nuclei in combination with a distinctly plasmacytic cytoplasm. Monoclonality was revealed by the cytoplasmic positively of the tumor cells for lambda chains only. This case strongly suggests that in at least a number of cases of lymphadenosis benigna cutis, a low-grade malignant lymphoma may be present.
ISSN:0340-3696
1432-069X